Protective actions of bioactive flavonoids chrysin and luteolin on the glyoxal induced formation of advanced glycation end products and aggregation of human serum albumin: In vitro and molecular docking analysis
The post-translational modification of proteins by nonenzymatic glycation (NEG) and the buildup of AGEs are the 2 underlying elements related to the long-term pathogenesis in diabetes. Glyoxal (GO) is a reactive intermediate which has the power to switch proteins and generate AGEs at a quicker fee. Human serum albumin (HSA) being probably the most ample …