The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide-Doxorubicin Binding to DNA

Matrix metalloproteinases (MMPs) are extracellular matrix degradation elements, selling most cancers development. Therefore, they might present an enzyme-assisted supply of doxorubicin (DOX) in most cancers remedy. Within the present research, the intercalation technique of DOX and tetrapeptide-DOX, the product of the MMPs’ cleavage of carrier-linked DOX, into dsDNA was investigated utilizing stationary and time-resolved fluorescence spectroscopy, UV-Vis spectrophotometry and isothermal titration calorimetry (ITC).

The molecular dynamics (MD) simulations on the identical tetrapeptide-DOX^…DNA and DOX^…DNA methods have been additionally carried out. The undertaken research point out that DOX and tetrapeptide-DOX can successfully bond with dsDNA via the intercalation mode; nonetheless, tetrapeptide-DOX kinds much less secure complexes than free DOX. Furthermore, the obtained outcomes show that the variations in DNA affinity of each types of DOX may be attributed to completely different intercalation modes.

Tetrapeptide-DOX exhibits a choice to intercalate into DNA via the main groove, whereas DOX does it via the minor one. In abstract, we are able to conclude that the tetrapeptide-DOX intercalation to DNA is critical and that even the dearth of non-specific proteases releasing DOX from the tetrapeptide conjugate, the presence of which is usually recommended by the literature for the environment friendly launch of DOX, mustn’t stop the cytostatic motion of the anthracycline.

Atmospheric strain photoionization versus electrospray for the dereplication of extremely conjugated pure merchandise utilizing molecular networks

Pure merchandise are sources of inspiration and reservoir of excessive priceless molecules. Not too long ago, analytical instruments based mostly on liquid chromatography coupled to tandem mass spectrometry to generate molecular community grew to become extensively employed for dereplication. This technique tremendously accelerates the identification of identified and structural speculation of unknown.

Regardless of the provision of various ionization sources, alternate options to classical electrospray ionization (ESI), comparable to atmospheric strain chemical ionization (APCI) or photoionization (APPI), have been uncared for. Specifically, APPI has been described for its ionization effectivity on non-polar molecules bearing no acid or primary teams. For that purpose, we investigated APPI potential to generate molecular community and evaluate it to ESI on a number of standards which are technology of ion species, sensitivity and signal-to-noise ratio (SNR) for various extracts wealthy in extremely conjugated pure merchandise.

We first optimized APPI experimental circumstances on crude extract from a fungus, Penicillium sclerotiorum, producing polyketones belonging to the azaphilone household. Then we in contrast APPI and ESI on completely different fractions of the fungus and on two plant extracts, French Guyanese Swartzia panacoco (Aubl.) R.S. Cowan (arial components) and Indian Cassia auriculata L. (leaves) containing phenolic compounds, comparable to flavonoids. Whereas ESI generated extra ion species and displayed a greater sensitivity, APPI generated solely protonated adduct and higher SNR. Evaluating ESI and APPI generated species on molecular community reveal that each methods overlap for almost all of protonated ions.

Cronobacter spp. remoted from aquatic merchandise in China: Incidence, antibiotic resistance, molecular attribute and CRISPR variety

Cronobacter species (Cronobacter spp.) are necessary foodborne pathogens that may infect and trigger severe life-threatening ailments in infants and immunocompromised aged. This research aimed to accumulate knowledge on Cronobacter spp. contamination of aquatic merchandise in China from 2011 to 2016. In whole, 800 aquatic merchandise have been examined, and the general contamination price for Cronobacter spp. was 3.9% (31/800). The common contamination stage of the constructive samples was 2.05 MPN/g. 4 species and 9 serotypes have been recognized amongst 33 isolates, of which the C. sakazakii serogroup O1 (n = 9) was the first serotype.

The vast majority of Cronobacter spp. strains harbored highest resistance in opposition to cephalothin (84.8%), adopted by tetracycline (6.1%), trimethoprim/sulfameth-oxazole (3.0%) and chloramphenicol (3.0%). Two isolates have been resistant to a few antibiotics. In whole, 26 sequence sorts and 33 CRISPR sorts (together with 6 new STs and 26 new CTs) have been recognized, which signifies the extraordinarily excessive variety of Cronobacter spp. in aquatic merchandise. Pathogenic C. sakazakii ST4, ST1, and C. malonaticus ST7 have been additionally noticed.

Total, this large-scale research revealed the comparatively low prevalence and excessive genetic variety of Cronobacter spp. in aquatic merchandise in China, and the findings present priceless data that may information the institution of efficient measures for the management and precaution of Cronobacter spp. in aquatic merchandise throughout manufacturing processes.

Prevalence, Antimicrobial Resistance and Molecular Range of Enterococcus faecium in Processed Pork Meat Merchandise in Korea

As a result of Enterococcus faecium is a crucial nosocomial pathogen and sentinel organism for monitoring antimicrobial resistance, data on the contamination and antimicrobial resistance patterns of E. faecium in meals are important to public well being and meals security.

We analyzed the incidence of E. faecium in retail pork meat merchandise (n = 124), and antimicrobial resistance of 30 E. faecium isolates have been examined in opposition to 14 antimicrobials utilizing the broth dilution check and disc diffusion check. Rep-PCR-based molecular variety was additionally analyzed utilizing Deviersilab. The very best contamination of enterococci was noticed for minced pork meat however many of the E. faecium was remoted from meatball-type frozen pork meat merchandise (FP).

Incidences of antimicrobial-resistant E. faecium in opposition to erythromycin, clindamycin and nitrofurantoin have been 80%, 50% and 20%, respectively. No vancomycin-resistant enterococci have been analyzed. Rep-PCR confirmed distinctive clusters with a similarity ≥ 98%, consisting of 18 E. faecium isolates from FP manufactured in seven corporations.

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA810A-1 components)
RA820A-1	SBI	20 profiles	EUR 1220

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA812A-1 components)
RA822A-1	SBI	20 profiles	EUR 1220

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA811A-1 components) 20 profiles
RA821A-1	SBI	20 profiles	EUR 1220

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA820TC-1	SBI	20 profiles	EUR 1533

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA821TC-1	SBI	20 profiles	EUR 1533

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800TC-1 with 50ml ExoQuick-TC, RA805A-1 and RA812A-1 components)
RA822TC-1	SBI	20 profiles	EUR 1533

SeraMir Control spike-in Small RNA and qPCR assay
RA805A-1	SBI	100 assays	EUR 181

Psoriasis Exosome RNA
P241-PS	101Bio	-	Ask for price

SeraMir 3'-Universal Primer (10,000 qPCR reactions)
RA800P-3	SBI	10,000 reactions	EUR 125

Lung Cancer Exosome RNA
P241-LG	101Bio	-	Ask for price

Leukemia - ALL Exosome RNA
P241-ALL	101Bio	-	Ask for price

Leukemia - AML Exosome RNA
P241-AML	101Bio	-	Ask for price

Leukemia - CLL Exosome RNA
P241-CLL	101Bio	-	Ask for price

Leukemia - CML Exosome RNA
P241-CML	101Bio	-	Ask for price

Liver Cancer Exosome RNA
P241-LV	101Bio	-	Ask for price

Normal human exosome RNA
P240	101Bio	-	EUR 1499

Breast Cancer Exosome RNA
P241-BR	101Bio	-	Ask for price

Crohn's Disease Exosome RNA
P241-CR	101Bio	-	Ask for price

Kidney Cancer Exosome RNA
P241-KN	101Bio	-	Ask for price

Bladder Cancer Exosome RNA
P241-BL	101Bio	-	Ask for price

Thyroid Cancer Exosome RNA
P241-TH	101Bio	-	Ask for price

Prostate Cancer Exosome RNA
P241-PR	101Bio	-	Ask for price

Colorectal Cancer Exosome RNA
P241-CO	101Bio	-	Ask for price

Rheumatoid Arthritis Exosome RNA
P241-RA	101Bio	-	Ask for price

Nasopharyngeal Cancer Exosome RNA
P241-NA	101Bio	-	Ask for price

Diabetes (Type 1) Exosome RNA
P241-DB1	101Bio	-	Ask for price

Diabetes (Type 2) Exosome RNA
P241-DB2	101Bio	-	Ask for price

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)
P101NGS	101Bio	-	Ask for price

Leukemia - Hairy Cell Exosome RNA
P241-HC	101Bio	-	Ask for price

Urine Exosome RNA Isolation Kit
47200	Norgen Biotek Corp	50 Preps	EUR 429

LiqBiopsy Tumor Exosome RNA Kit
K1254-24	Biovision	each	EUR 1332

Melanoma (skin cancer) Exosome RNA
P241-MN	101Bio	-	Ask for price

Uterine Corpus Cancer Exosome RNA
P241-UT	101Bio	-	Ask for price

Non-Hodgkin lymphoma Exosome RNA
P241-NH	101Bio	-	Ask for price

Exosome electron microscopy imaging (EM)
S109	101Bio	-	EUR 600

Uterine Cervical Cancer Exosome RNA
P241-UC	101Bio	-	Ask for price

Leukemia - Multiple Myeloma Exosome RNA
P241-MM	101Bio	-	Ask for price

Systemic Lupus Erythematosus Exosome RNA
P241-SL	101Bio	-	Ask for price

ExoQualiTM Exosome RNA Extraction Kit (Plasma & Serum)
CEIK-093L-30T	Creative Bioarray	30T	Ask for price

ExoQualiTM Exosome RNA Extraction Kit (Plasma & Serum)
CEIK-093L-50T	Creative Bioarray	50T	Ask for price

Exosome RNA Helicase MTR4 (MTR4) Antibody
abx149899-100ug	Abbexa	100 ug	EUR 526.8

ExoQuick Exosome RNA Column Purification kit
EQ808A-1	SBI	20 preps	EUR 344

ExoQualiTM Exosome RNA Extraction Kit (Pre-Isolated Exosomes)
CEIK-051L-30T	Creative Bioarray	30T	Ask for price

ExoQualiTM Exosome RNA Extraction Kit (Pre-Isolated Exosomes)
CEIK-051L-50T	Creative Bioarray	50T	Ask for price

Exosome RNA Helicase MTR4 (MTR4/SKIV2L2) Antibody
abx004268-100l	Abbexa	100 µl	EUR 400

Exosome RNA Helicase MTR4 (MTR4/SKIV2L2) Antibody
20-abx004268	Abbexa	Ask for price Ask for price Ask for price Ask for price	20 ul 50 ul 100 ul 200 ul

Exosome RNA Helicase MTR4 (MTR4/SKIV2L2) Antibody
abx004268-20l	Abbexa	20 µl	EUR 175

Exosome RNA Helicase MTR4 (MTR4/SKIV2L2) Antibody
abx004268-50l	Abbexa	50 µl	EUR 275

Exosomal RNA Isolation Kit (for use with Urine Exosome Purification Kits or Plasma/Serum Exosome Purification Kits)
58000	Norgen Biotek Corp	50 Preps	EUR 243

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-10	Biovision	each	EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-20	Biovision	each	EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-3	Biovision	each	EUR 523.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum)
M1038-5	Biovision	each	EUR 796.8

ExoQualiTM Exosome RNA Extraction Kit (Urine & Cell Supernatant)
CEIK-094L-10T	Creative Bioarray	10T	Ask for price

ExoQualiTM Exosome RNA Extraction Kit (Urine & Cell Supernatant)
CEIK-094L-20T	Creative Bioarray	20T	Ask for price

Plasma/Serum Exosome Purification and RNA Isolation Mini Kit
58300	Norgen Biotek Corp	50 Preps	EUR 627

Plasma/Serum Exosome Purification and RNA Isolation Midi Kit
58500	Norgen Biotek Corp	25 Preps	EUR 569.4

Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit
58600	Norgen Biotek Corp	15 Preps	EUR 341.4

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7)
MBS6005385-01mg	MyBiosource	0.1(mg	EUR 630

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7)
MBS6005385-5x01mg	MyBiosource	5x0.1mg	EUR 2680

Puck Separator Tools
M-CP-111-028	MiTeGen	1 UNIT	EUR 305
Description: Puck Separator Tools

Puck Separator Tools
X-CC-116	Jena Bioscience GmbH	1pc.	EUR 482.44

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (PE)
MBS6157711-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (PE)
MBS6157711-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (AP)
MBS6131196-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (AP)
MBS6131196-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) APC
MBS6136499-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) APC
MBS6136499-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (FITC)
MBS6147105-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (FITC)
MBS6147105-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (HRP)
MBS6152408-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (HRP)
MBS6152408-5x01mL	MyBiosource	5x0.1mL	EUR 3800

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 10 reactions)
M1039-10	Biovision	each	EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 20 reactions)
M1039-20	Biovision	each	EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 3 reactions)
M1039-3	Biovision	each	EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, plasma, urine, serum, 5 reactions)
M1039-5	Biovision	each	EUR 796.8

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (Biotin)
MBS6141802-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (Biotin)
MBS6141802-5x01mL	MyBiosource	5x0.1mL	EUR 3800

Exosome (Pre-isolated) RNA Extraction kit Note! This kit doesn't contain the conponents for exosome enrichment.
EIRK-01	Creative Biolabs	50 reactions	EUR 3380.4
Description: A RNA Extraction kit that is ideal for total RNA (miRNA+mRNAs) extraction from pre-isolated exosomes.

Urine Exosome Purification and RNA Isolation Mini Kit
58400	Norgen Biotek Corp	50 Preps	EUR 843

Urine Exosome Purification and RNA Isolation Midi Kit
58700	Norgen Biotek Corp	25 Preps	EUR 797.4

Urine Exosome Purification and RNA Isolation Maxi Kit
58800	Norgen Biotek Corp	15 Preps	EUR 479.4

microRNA mimics
GC0092	GenCefe Co Ltd	5 nmol/2 OD	EUR 48.95

microRNA agomiR
GC0096	GenCefe Co Ltd	5 nmol/2 OD	EUR 87.45

Plasma/Serum Exosome and Free-Circulating RNA Isolation Mini Kit
59500	Norgen Biotek Corp	50 Preps	EUR 797.4

Plasma/Serum Exosome and Free-Circulating RNA Isolation Midi Kit
59600	Norgen Biotek Corp	25 Preps	EUR 683.4

Plasma/Serum Exosome and Free-Circulating RNA Isolation Maxi Kit
59700	Norgen Biotek Corp	15 Preps	EUR 513

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 650)
MBS6222084-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 650)
MBS6222084-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 490)
MBS6200734-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 490)
MBS6200734-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 405)
MBS6190059-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 405)
MBS6190059-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 550)
MBS6211409-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 550)
MBS6211409-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 750)
MBS6232759-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC2 (Exosome Complex Component RRP4, Exosome Component 2, Ribosomal RNA-processing Protein 4, RRP4, p7) (MaxLight 750)
MBS6232759-5x01mL	MyBiosource	5x0.1mL	EUR 3800

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)
M1030-10	Biovision	each	EUR 1005.6

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)
M1030-20	Biovision	each	EUR 1546.8

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)
M1030-3	Biovision	each	EUR 529.2

ExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)
M1030-5	Biovision	each	EUR 796.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 10 reactions)
M1031-10	Biovision	each	EUR 1005.6

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 20 reactions)
M1031-20	Biovision	each	EUR 1546.8

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 3 reactions)
M1031-3	Biovision	each	EUR 523.2

ExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, cell media, 5 reactions)
M1031-5	Biovision	each	EUR 796.8

microRNA inhibitor
GC0093	GenCefe Co Ltd	10 nmol/2 OD	EUR 48.95

microRNA antagomiR
GC0097	GenCefe Co Ltd	10 nmol/2 OD	EUR 87.45

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A)
MBS6012273-02mL	MyBiosource	0.2(mL	EUR 695

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A)
MBS6012273-5x02mL	MyBiosource	5x0.2mL	EUR 2975

EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Mini Kit
73100	Norgen Biotek Corp	50 Preps	EUR 783

EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Midi Kit
73110	Norgen Biotek Corp	25 Preps	EUR 711

EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit
73120	Norgen Biotek Corp	15 Preps	EUR 426.6

microRNA-21-IN-2
HY-151516	MedChemExpress	10 mg	EUR 346.33
Description: microRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. microRNA-21-IN-2 can be used for the research of cancer[1].

microRNA-21-IN-3
HY-153534	MedChemExpress	1 mg	EUR 2056.31
Description: microRNA-21-IN-3 (compound 45) can specifically bind to the precursor of oncogenic and pro-inflammatory microRNA-21 with medium nanomolar affinity, reduce cancer cell proliferation and miR-21 levels, and can be used in antitumor research[1].

microRNA-21-IN-1
HY-146411	MedChemExpress	1 mg	EUR 2943.77
Description: microRNA-21-IN-1 (compound 7A) is an efficient microRNA inhibitor. microRNA-21-IN-1 has antiproliferative activity against Hela and HCT-116 cells with IC50s of 5.5 μM and 2.8 μM respectively, as well as promotes apoptosis of Hela cells. microRNA-21-IN-1 upregulates the expression of microRNA-21 downstream functional targets (PTEN, EGR1 and SLIT2). microRNA-21-IN-1 can be used for researching anticancer[1].

microRNA-21-IN-1
T63879-10mg	TargetMol Chemicals	10mg	Ask for price
Description: microRNA-21-IN-1

microRNA-21-IN-1
T63879-1g	TargetMol Chemicals	1g	Ask for price
Description: microRNA-21-IN-1

microRNA-21-IN-1
T63879-1mg	TargetMol Chemicals	1mg	Ask for price
Description: microRNA-21-IN-1

microRNA-21-IN-1
T63879-50mg	TargetMol Chemicals	50mg	Ask for price
Description: microRNA-21-IN-1

microRNA-21-IN-1
T63879-5mg	TargetMol Chemicals	5mg	Ask for price
Description: microRNA-21-IN-1

microRNA-21-IN-2
T61093-10mg	TargetMol Chemicals	10mg	Ask for price
Description: microRNA-21-IN-2

microRNA-21-IN-2
T61093-1g	TargetMol Chemicals	1g	Ask for price
Description: microRNA-21-IN-2

microRNA-21-IN-2
T61093-1mg	TargetMol Chemicals	1mg	Ask for price
Description: microRNA-21-IN-2

microRNA-21-IN-2
T61093-50mg	TargetMol Chemicals	50mg	Ask for price
Description: microRNA-21-IN-2

microRNA-21-IN-2
T61093-5mg	TargetMol Chemicals	5mg	Ask for price
Description: microRNA-21-IN-2

ExoQuick Exosome Isolation and RNA Purification kit (for Serum and Plasma)
EQ806A-1	SBI	20 preps	EUR 493

Urine Exosome and Free-Circulating RNA Isolation Mini Kit
59200	Norgen Biotek Corp	50 Preps	EUR 941.4

Urine Exosome and Free-Circulating RNA Isolation Midi Kit
59300	Norgen Biotek Corp	25 Preps	EUR 843

Urine Exosome and Free-Circulating RNA Isolation Maxi Kit
59400	Norgen Biotek Corp	15 Preps	EUR 641.4

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (AP)
MBS6297141-02mL	MyBiosource	0.2mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (AP)
MBS6297141-5x02mL	MyBiosource	5x0.2mL	EUR 4250

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (APC)
MBS6297142-02mL	MyBiosource	0.2mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (APC)
MBS6297142-5x02mL	MyBiosource	5x0.2mL	EUR 4250

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (PE)
MBS6297151-02mL	MyBiosource	0.2mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (PE)
MBS6297151-5x02mL	MyBiosource	5x0.2mL	EUR 4250

microRNA mimics N.C
GC0094	GenCefe Co Ltd	5 nmol/2 OD	EUR 31.05

microRNA agomiR N.C
GC0098	GenCefe Co Ltd	5 nmol/2 OD	EUR 58.05

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (Biotin)
MBS6297143-02mL	MyBiosource	0.2mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (Biotin)
MBS6297143-5x02mL	MyBiosource	5x0.2mL	EUR 4250

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (FITC)
MBS6297144-02mL	MyBiosource	0.2mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (FITC)
MBS6297144-5x02mL	MyBiosource	5x0.2mL	EUR 4250

Total Exosome RNA Extraction Kit (Biological Fluids/Culture Media Supplement)
EIRK-03	Creative Biolabs	20 reactions	EUR 3380.4
Description: This product is a useful tool for the isolation and efficient total RNA (miRNA and mRNAs) extraction from the total exosome population from human biofluids or cell culture media.

microRNA inhibitor N.C
GC0095	GenCefe Co Ltd	10 nmol/2 OD	EUR 31.05

microRNA antagomiR N.C
GC0099	GenCefe Co Ltd	10 nmol/2 OD	EUR 58.05

EXTRAClean Urine Exosome Purification and RNA Isolation Midi Kit
73200	Norgen Biotek Corp	25 Preps	EUR 996.6

EXTRAClean Urine Exosome Purification and RNA Isolation Mini Kit
73210	Norgen Biotek Corp	50 Preps	EUR 1053

EXTRAClean Urine Exosome Purification and RNA Isolation Maxi Kit
73220	Norgen Biotek Corp	15 Preps	EUR 599.4

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p)
MBS643286-01mg	MyBiosource	0.1mg	EUR 630

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p)
MBS643286-5x01mg	MyBiosource	5x0.1mg	EUR 2680

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p)
MBS644364-005mg	MyBiosource	0.05mg	EUR 630

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p)
MBS644364-5x005mg	MyBiosource	5x0.05mg	EUR 2680

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)
P101EZ	101Bio	-	Ask for price

EXTRAClean Plasma/Serum Exosome and Free-Circulating RNA Isolation Mini Kit
73400	Norgen Biotek Corp	50 Preps	EUR 996.6

EXTRAClean Plasma/Serum Exosome and Free-Circulating RNA Isolation Midi Kit
73410	Norgen Biotek Corp	25 Preps	EUR 853.8

EXTRAClean Plasma/Serum Exosome and Free-Circulating RNA Isolation Maxi Kit
73420	Norgen Biotek Corp	15 Preps	EUR 641.4

Psoriasis Exosome
P141-PS	101Bio	-	Ask for price

Kinesis Siltite Micron union 0.4 to 0.5 kit inclides 5 X ferrules and necessary tools - EACH
CHR1923	Scientific Laboratory Supplies	EACH	EUR 243

plastic tools type CP - EACH
INS2196	Scientific Laboratory Supplies	EACH	EUR 39.95

plastic tools type SV - EACH
INS2198	Scientific Laboratory Supplies	EACH	EUR 30.11

TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 10 reactions)
M1032-10	Biovision	each	EUR 1057.2

TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions)
M1032-20	Biovision	each	EUR 1618.8

TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions)
M1032-3	Biovision	each	EUR 523.2

TumorExoPure? 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 5 reactions)
M1032-5	Biovision	each	EUR 796.8

TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 10 reactions)
M1033-10	Biovision	each	EUR 1057.2

TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 20 reactions)
M1033-20	Biovision	each	EUR 1618.8

TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 3 reactions)
M1033-3	Biovision	each	EUR 523.2

TumorExoPure? 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 5 reactions)
M1033-5	Biovision	each	EUR 796.8

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 10 reactions)
M1034-10	Biovision	each	EUR 1005.6

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions)
M1034-20	Biovision	each	EUR 1495.2

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions)
M1034-3	Biovision	each	EUR 398.4

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 5 reactions)
M1034-5	Biovision	each	EUR 777.6

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 10 reactions)
M1035-10	Biovision	each	EUR 1005.6

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 20 reactions)
M1035-20	Biovision	each	EUR 1495.2

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 3 reactions)
M1035-3	Biovision	each	EUR 516

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse biofluids, 5 reactions)
M1035-5	Biovision	each	EUR 777.6

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 405)
MBS6297146-01mL	MyBiosource	0.1mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 405)
MBS6297146-5x01mL	MyBiosource	5x0.1mL	EUR 4250

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 490)
MBS6297147-01mL	MyBiosource	0.1mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 490)
MBS6297147-5x01mL	MyBiosource	5x0.1mL	EUR 4250

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 550)
MBS6297148-01mL	MyBiosource	0.1mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 550)
MBS6297148-5x01mL	MyBiosource	5x0.1mL	EUR 4250

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 650)
MBS6297149-01mL	MyBiosource	0.1mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 650)
MBS6297149-5x01mL	MyBiosource	5x0.1mL	EUR 4250

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 750)
MBS6297150-01mL	MyBiosource	0.1mL	EUR 980

EXOSC4, ID (EXOSC4, RRP41, SKI6, Exosome complex component RRP41, Exosome component 4, Ribosomal RNA-processing protein 41, p12A) (MaxLight 750)
MBS6297150-5x01mL	MyBiosource	5x0.1mL	EUR 4250

microRNA Purification Kit
21300	Norgen Biotek Corp	25 Preps	EUR 149.4

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (PE)
MBS6157715-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (PE)
MBS6157715-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (AP)
MBS6131200-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (AP)
MBS6131200-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) APC
MBS6136503-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) APC
MBS6136503-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (FITC)
MBS6147109-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (FITC)
MBS6147109-5x01mL	MyBiosource	5x0.1mL	EUR 3800

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (HRP)
MBS6152412-01mL	MyBiosource	0.1(mL	EUR 875

EXOSC7 (Exosome Complex Exonuclease RRP42, Ribosomal RNA-processing Protein 42, Exosome Component 7, p8, KIAA0116, RRP42, FLJ26543, hRrp42p) (HRP)
MBS6152412-5x01mL	MyBiosource	5x0.1mL	EUR 3800

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions)
M1036-10	Biovision	each	EUR 1005.6

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 20 reactions)
M1036-20	Biovision	each	EUR 1546.8

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 3 reactions)
M1036-3	Biovision	each	EUR 516

MouseExoPure? 0.4 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 5 reactions)
M1036-5	Biovision	each	EUR 777.6

MouseExoPure? 1.0 micron Immunobeads (Overall Exosome Isolation, mouse cell media, 10 reactions)
M1037-10	Biovision	each	EUR 1005.6

The analyzed knowledge on the contamination and antimicrobial resistance patterns mixed with molecular typing may be helpful to derive threat administration of antimicrobial-resistant enterococci in meals.