The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide-Doxorubicin Binding to DNA

Matrix metalloproteinases (MMPs) are extracellular matrix degradation elements, selling most cancers development. Therefore, they might present an enzyme-assisted supply of doxorubicin (DOX) in most cancers remedy. Within the present research, the intercalation technique of DOX and tetrapeptide-DOX, the product of the MMPs’ cleavage of carrier-linked DOX, into dsDNA was investigated utilizing stationary and time-resolved fluorescence spectroscopy, UV-Vis spectrophotometry and isothermal titration calorimetry (ITC).

The molecular dynamics (MD) simulations on the identical tetrapeptide-DOX^…DNA and DOX^…DNA methods have been additionally carried out. The undertaken research point out that DOX and tetrapeptide-DOX can successfully bond with dsDNA via the intercalation mode; nonetheless, tetrapeptide-DOX kinds much less secure complexes than free DOX. Furthermore, the obtained outcomes show that the variations in DNA affinity of each types of DOX may be attributed to completely different intercalation modes.

Tetrapeptide-DOX exhibits a choice to intercalate into DNA via the main groove, whereas DOX does it via the minor one. In abstract, we are able to conclude that the tetrapeptide-DOX intercalation to DNA is critical and that even the dearth of non-specific proteases releasing DOX from the tetrapeptide conjugate, the presence of which is usually recommended by the literature for the environment friendly launch of DOX, mustn’t stop the cytostatic motion of the anthracycline.

Atmospheric strain photoionization versus electrospray for the dereplication of extremely conjugated pure merchandise utilizing molecular networks

Pure merchandise are sources of inspiration and reservoir of excessive priceless molecules. Not too long ago, analytical instruments based mostly on liquid chromatography coupled to tandem mass spectrometry to generate molecular community grew to become extensively employed for dereplication. This technique tremendously accelerates the identification of identified and structural speculation of unknown.

Regardless of the provision of various ionization sources, alternate options to classical electrospray ionization (ESI), comparable to atmospheric strain chemical ionization (APCI) or photoionization (APPI), have been uncared for. Specifically, APPI has been described for its ionization effectivity on non-polar molecules bearing no acid or primary teams. For that purpose, we investigated APPI potential to generate molecular community and evaluate it to ESI on a number of standards which are technology of ion species, sensitivity and signal-to-noise ratio (SNR) for various extracts wealthy in extremely conjugated pure merchandise.

We first optimized APPI experimental circumstances on crude extract from a fungus, Penicillium sclerotiorum, producing polyketones belonging to the azaphilone household. Then we in contrast APPI and ESI on completely different fractions of the fungus and on two plant extracts, French Guyanese Swartzia panacoco (Aubl.) R.S. Cowan (arial components) and Indian Cassia auriculata L. (leaves) containing phenolic compounds, comparable to flavonoids. Whereas ESI generated extra ion species and displayed a greater sensitivity, APPI generated solely protonated adduct and higher SNR. Evaluating ESI and APPI generated species on molecular community reveal that each methods overlap for almost all of protonated ions.

Cronobacter spp. remoted from aquatic merchandise in China: Incidence, antibiotic resistance, molecular attribute and CRISPR variety

Cronobacter species (Cronobacter spp.) are necessary foodborne pathogens that may infect and trigger severe life-threatening ailments in infants and immunocompromised aged. This research aimed to accumulate knowledge on Cronobacter spp. contamination of aquatic merchandise in China from 2011 to 2016. In whole, 800 aquatic merchandise have been examined, and the general contamination price for Cronobacter spp. was 3.9% (31/800). The common contamination stage of the constructive samples was 2.05 MPN/g. 4 species and 9 serotypes have been recognized amongst 33 isolates, of which the C. sakazakii serogroup O1 (n = 9) was the first serotype.

The vast majority of Cronobacter spp. strains harbored highest resistance in opposition to cephalothin (84.8%), adopted by tetracycline (6.1%), trimethoprim/sulfameth-oxazole (3.0%) and chloramphenicol (3.0%). Two isolates have been resistant to a few antibiotics. In whole, 26 sequence sorts and 33 CRISPR sorts (together with 6 new STs and 26 new CTs) have been recognized, which signifies the extraordinarily excessive variety of Cronobacter spp. in aquatic merchandise. Pathogenic C. sakazakii ST4, ST1, and C. malonaticus ST7 have been additionally noticed.

Total, this large-scale research revealed the comparatively low prevalence and excessive genetic variety of Cronobacter spp. in aquatic merchandise in China, and the findings present priceless data that may information the institution of efficient measures for the management and precaution of Cronobacter spp. in aquatic merchandise throughout manufacturing processes.

Prevalence, Antimicrobial Resistance and Molecular Range of Enterococcus faecium in Processed Pork Meat Merchandise in Korea

As a result of Enterococcus faecium is a crucial nosocomial pathogen and sentinel organism for monitoring antimicrobial resistance, data on the contamination and antimicrobial resistance patterns of E. faecium in meals are important to public well being and meals security.

We analyzed the incidence of E. faecium in retail pork meat merchandise (n = 124), and antimicrobial resistance of 30 E. faecium isolates have been examined in opposition to 14 antimicrobials utilizing the broth dilution check and disc diffusion check. Rep-PCR-based molecular variety was additionally analyzed utilizing Deviersilab. The very best contamination of enterococci was noticed for minced pork meat however many of the E. faecium was remoted from meatball-type frozen pork meat merchandise (FP).

Incidences of antimicrobial-resistant E. faecium in opposition to erythromycin, clindamycin and nitrofurantoin have been 80%, 50% and 20%, respectively. No vancomycin-resistant enterococci have been analyzed. Rep-PCR confirmed distinctive clusters with a similarity ≥ 98%, consisting of 18 E. faecium isolates from FP manufactured in seven corporations.

Navy RNA Lysis Kit 50
NAVYE1-RNA	Next Advance	50pack	EUR 237.6
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RNA Lysis Kit 250
NAVYE5-RNA	Next Advance	250pack	EUR 781.2
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Green RNA Lysis Kit 50
GREENE1-RNA	Next Advance	50pack	EUR 216
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RNA Lysis Kit 250
GREENE5-RNA	Next Advance	250pack	EUR 685.2
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Pink RNA Lysis Kit 50
PINKE1-RNA	Next Advance	50pack	EUR 213.6
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 250
PINKE5-RNA	Next Advance	250pack	EUR 673.2
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 50
REDE1-RNA	Next Advance	50pack	EUR 230.4
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 250
REDE5-RNA	Next Advance	250pack	EUR 746.4
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 50
YELLOWE1-RNA	Next Advance	50pack	EUR 230.4
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 250
YELLOWE5-RNA	Next Advance	250pack	EUR 748.8
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

LiqBiopsy Tumor Exosome RNA Kit
K1254-24	Biovision	each	EUR 1332

5E Navy RNA Lysis Kit 100
NAVY5E100-RNA	Next Advance	100pack	EUR 543.6
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

5E Navy RNA Lysis Kit 20
NAVY5E20-RNA	Next Advance	20pack	EUR 183.6
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 50
NAVYR1-RNA	Next Advance	50pack	EUR 242.4
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 250
NAVYR5-RNA	Next Advance	250pack	EUR 799.2
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

5E GREEN RNA Lysis Kit 100
GREEN5E100-RNA	Next Advance	100pack	EUR 463.2
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

5E GREEN RNA Lysis Kit 20
GREEN5E20-RNA	Next Advance	20pack	EUR 165.6
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 50
GREENR1-RNA	Next Advance	50pack	EUR 220.8
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 250
GREENR5-RNA	Next Advance	250pack	EUR 704.4
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

5E PINK RNA Lysis Kit 100
PINK5E100-RNA	Next Advance	100pack	EUR 456
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E PINK RNA Lysis Kit 20
PINK5E20-RNA	Next Advance	20pack	EUR 163.2
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 50
PINKR1-RNA	Next Advance	50pack	EUR 217.2
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 250
PINKR5-RNA	Next Advance	250pack	EUR 691.2
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 100
RED5E100-RNA	Next Advance	100pack	EUR 514.8
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 20
RED5E20-RNA	Next Advance	20pack	EUR 177.6
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 50
REDR1-RNA	Next Advance	50pack	EUR 234
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 250
REDR5-RNA	Next Advance	250pack	EUR 765.6
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 50
YELLOWR1-RNA	Next Advance	50pack	EUR 238.8
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 250
YELLOWR5-RNA	Next Advance	250pack	EUR 787.2
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

SeraMir Control spike-in Small RNA and qPCR assay
RA805A-1	SBI	100 assays	EUR 282

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA810A-1 components)
RA820A-1	SBI	20 profiles	EUR 1556.4

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA812A-1 components)
RA822A-1	SBI	20 profiles	EUR 1556.4

Puck Separator Tools
M-CP-111-028	MiTeGen	1 UNIT	EUR 305
Description: Puck Separator Tools

ExoQuick Exosome RNA Column Purification kit
EQ808A-1	SBI	20 preps	EUR 482.4

Exosome RNA Helicase MTR4 (MTR4) Antibody
abx149899-100ug	Abbexa	100 ug	EUR 526.8

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA811A-1 components) 20 profiles
RA821A-1	SBI	20 profiles	EUR 1556.4

plastic tools type CP
INS2196	Scientific Laboratory Supplies	EACH	EUR 26.56

plastic tools type SV
INS2198	Scientific Laboratory Supplies	EACH	EUR 19.95

Exosome RNA Helicase MTR4 (MTR4/SKIV2L2) Antibody
20-abx004268	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

plastic tools CP Rounded body
INS2184	Scientific Laboratory Supplies	EACH	EUR 8.89

plastic tools SV Rounded body
INS2186	Scientific Laboratory Supplies	EACH	EUR 6.61

plastic tools CP Squared body
INS2188	Scientific Laboratory Supplies	EACH	EUR 8.89

plastic tools SV Squared body
INS2190	Scientific Laboratory Supplies	EACH	EUR 6.61

plastic tools CP Squared body
INS2192	Scientific Laboratory Supplies	EACH	EUR 8.89

plastic tools SV Squared body
INS2194	Scientific Laboratory Supplies	EACH	EUR 6.61

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA820TC-1	SBI	20 profiles	EUR 1941.6

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA821TC-1	SBI	20 profiles	EUR 1941.6

Exosome (Pre-isolated) RNA Extraction kit Note! This kit doesn't contain the conponents for exosome enrichment.
EIRK-01	Creative Biolabs	50 reactions	EUR 3380.4
Description: A RNA Extraction kit that is ideal for total RNA (miRNA+mRNAs) extraction from pre-isolated exosomes.

Total Exosome RNA Extraction Kit (Biological Fluids/Culture Media Supplement)
EIRK-03	Creative Biolabs	20 reactions	EUR 3380.4
Description: This product is a useful tool for the isolation and efficient total RNA (miRNA and mRNAs) extraction from the total exosome population from human biofluids or cell culture media.

SeraMir 3'-Universal Primer (10,000 qPCR reactions)
RA800P-3	SBI	10,000 reactions	EUR 213.6

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800TC-1 with 50ml ExoQuick-TC, RA805A-1 and RA812A-1 components)
RA822TC-1	SBI	20 profiles	EUR 1941.6

ExoQuick Exosome Isolation and RNA Purification kit (for Serum and Plasma)
EQ806A-1	SBI	20 preps	EUR 664.8

ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media)
EQ806TC-1	SBI	10 preps	EUR 664.8

TumorExoRNA? Tumor-derived exosome immunocapture and RNA extraction kit (10 reactions)
K1221-10	Biovision	each	EUR 992.4

TumorExoRNA? Tumor-derived exosome immunocapture and RNA extraction kit (20 reactions)
K1221-20	Biovision	each	EUR 1462.8

Lyophilized Exosome Standards
ExoA375	ImmunoStep	100 μg	EUR 364.2

Lyophilized Exosome Standards
ExoHT29	ImmunoStep	100 μg	EUR 364.2

Lyophilized Exosome Standards
ExoMCF7	ImmunoStep	100 μg	EUR 364.2

Lyophilized Exosome Standards
ExoPC3	ImmunoStep	100 μg	EUR 364.2

Lyophilized Exosome Standards
ExoPLASMA	ImmunoStep	100 μg	EUR 364.2

Lyophilized Exosome Standards
ExoUrine	ImmunoStep	100 μg	EUR 364.2

Exosome precipitation Solution
EPStep	ImmunoStep	12 ml	EUR 333

MicroRNA Isolation Kit
KS341025	Biochain	1 kit	EUR 307.2
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

TotalExoRNA? Overall exosome immunocapture and RNA extraction kit (Biological Fluids/Cell Media, 20 reactions)
K1220-20	Biovision	each	EUR 1462.8

FluoroCet Exosome Quantitation Kit
FCET96A-1	SBI	96 reactions	EUR 871.2

Fluorescent Exosome Standard (Urine )
ESF-15	Creative Biolabs	100 µg	EUR 2067.6
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling.

EXOCET Exosome Quantitation Kit
EXOCET96A-1	SBI	96 reactions	EUR 625.2

Exosome Component 9 Peptide
46-967P	ProSci	0.1 mg	EUR 405.6
Description: (CT) PMSCL1 Peptide

Exosome Component 5 Protein
20-abx260873	Abbexa	EUR 4101.60 EUR 393.60 EUR 276.00	1 mg 25 ug 5 ug

Exosome Component 7 Protein
20-abx261347	Abbexa	EUR 4101.60 EUR 393.60 EUR 276.00	1 mg 20 ug 5 ug

Exosome Component 10 Protein
20-abx261805	Abbexa	EUR 5238.00 EUR 393.60 EUR 276.00	1 mg 20 ug 5 ug

Exosome Component 4 Protein
20-abx261954	Abbexa	EUR 5388.00 EUR 393.60 EUR 276.00	1 mg 20 ug 5 ug

Exosome Component 9 Protein
20-abx262123	Abbexa	EUR 393.60 EUR 6106.80 EUR 276.00	10 ug 1 mg 2 µg

Exosome Component 8 Protein
20-abx262850	Abbexa	EUR 393.60 EUR 7676.40 EUR 276.00	10 ug 1 mg 2 µg

Exosome Component 3 Protein
20-abx263422	Abbexa	EUR 276.00 EUR 1930.80 EUR 393.60	1 µg 50 ug 5 ug

Exosome Component 1 Protein
20-abx263423	Abbexa	EUR 1930.80 EUR 393.60 EUR 276.00	100 ug 10 ug 2 µg

Orange Lysis Kit 50
ORANGEE1-RNA	Next Advance	50pack	EUR 198
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange Lysis Kit 250
ORANGEE5-RNA	Next Advance	250pack	EUR 644.4
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 50
ORANGER1-RNA	Next Advance	50pack	EUR 202.8
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 250
ORANGER5-RNA	Next Advance	250pack	EUR 664.8
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Measuring Spoon 100 RNase Free
MSP01-RNA	Next Advance	10pack	EUR 158.4
Description: 100uL (0.1mL) measuring spoon. Ideal for aliquoting beads into tubes. RNase free.

Measuring Spoon 500 RNase Free
MSP05-RNA	Next Advance	10pack	EUR 163.2
Description: 500uL (0.5mL) measuring spoon. Ideal for aliquoting beads into tubes. RNase free.

Glass Beads 0.1mm RNase Free
GB01-RNA	Next Advance	1pack	EUR 115.2
Description: Glass beads. 0.1mm. 4mL. RNase free.

Glass Beads 0.5mm RNase Free
GB05-RNA	Next Advance	1pack	EUR 115.2
Description: Glass beads. 0.5mm. 4mL. RNase free.

Stainless Steel Beads 0.2mm RNase Free
SSB02-RNA	Next Advance	1pack	EUR 145.2
Description: Stainless steel beads. 0.2mm. 4mL. RNase free.

Stainless Steel Beads 0.5mm RNase Free
SSB05-RNA	Next Advance	1pack	EUR 145.2
Description: Stainless steel beads. 0.5mm. 4mL. RNase free.

Stainless Steel Beads 0.9 - 2.0mm blend RNase Free
SSB14B-RNA	Next Advance	1pack	EUR 153.6
Description: Stainless steel beads. 0.9 - 2.0mm. 4mL. RNase free.

Stainless Steel Beads 1.6mm RNase Free
SSB16-RNA	Next Advance	1pack	EUR 153.6
Description: Stainless steel beads. 1.6mm. 4mL. RNase free.

Stainless Steel Beads 3.2mm RNase Free
SSB32-RNA	Next Advance	1pack	EUR 212.4
Description: Stainless steel beads. 3.2mm. 10mL. RNase free.

Stainless Steel Beads 4.8mm RNase Free
SSB48-RNA	Next Advance	1pack	EUR 212.4
Description: Stainless steel beads. 4.8mm. 10mL. RNase free.

Stainless Steel Beads 6.0mm RNase Free
SSB60-RNA	Next Advance	1pack	EUR 214.8
Description: Stainless steel beads. 6.0mm. 10mL. RNase free.

Stainless Steel UFO Beads 3.5mm RNase Free
SSUFO35-RNA	Next Advance	1pack	EUR 226.8
Description: Stainless steel UFO beads. 3.5mm. 10mL. RNase free.

Stainless Steel UFO Beads 5.6mm RNase Free
SSUFO56-RNA	Next Advance	1pack	EUR 228
Description: Stainless steel UFO beads. 5.6mm. 10mL. RNase free.

Zirconium Oxide Beads 0.15mm RNase Free
ZrOB015-RNA	Next Advance	1pack	EUR 127.2
Description: Fused Zirconium Oxide beads . 0.15mm. 4mL. RNase-free.

Zirconium Oxide Beads 0.5mm RNase Free
ZrOB05-RNA	Next Advance	1pack	EUR 127.2
Description: Zirconium Oxide beads . 0.5mm. 4mL. RNase-free.

Zirconium Oxide Beads 1.0mm RNase Free
ZrOB10-RNA	Next Advance	1pack	EUR 128.4
Description: Zirconium Oxide beads . 1.0mm. 4mL. RNase-free.

Zirconium Oxide Beads 2.0mm RNase Free
ZrOB20-RNA	Next Advance	1pack	EUR 128.4
Description: Zirconium Oxide beads . 2.0mm. 4mL. RNase-free.

Cancer MicroRNA qPCR Array
RA610A-1	SBI	10 profiles	EUR 1406.4

Lyophilized Exosome Standard (Human Plasma)
ESL-25	Creative Biolabs	30 µgx2 vials	EUR 1604.4
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Lyophilized Exosome Standard (Human Saliva)
ESL-27	Creative Biolabs	30 µgx6 vials	EUR 3627.6
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Lyophilized Exosome Standard (Human Urine)
ESL-29	Creative Biolabs	30 µgx2 vials	EUR 1620
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Lyophilized Exosome Standard (Human Serum)
ESL-32	Creative Biolabs	30 µgx2 vials	EUR 1620
Description: Lyophilized exosomes can be used as control standards for FACS, WB, ELISA and as calibration standards for quantitation of exosome-derived markers from biological samples.

Exo-Fect Exosome Transfection Kit
EXFT10A-1	SBI	10 reactions	EUR 351.6

Exo-Fect Exosome Transfection Kit
EXFT20A-1	SBI	20 reactions	EUR 586.8

Exosome-depleted FBS Media Supplement
EXO-FBS-250A-1	SBI	250 ml	EUR 1057.2

Exosome-depleted FBS Media Supplement
EXO-FBS-50A-1	SBI	50 ml	EUR 289.2

Exo-FITC Exosome FACS stain
EXOFLOW800A-1	SBI	20 reactions	EUR 289.2

Exo-APC Exosome FACS stain
EXOFLOW810A-1	SBI	20 reactions	EUR 289.2

Exo-Check Exosome Antibody Array
EXORAY200A-4	SBI	4 arrays	EUR 648

Exo-Check Exosome Antibody Array
EXORAY210A-8	SBI	8 arrays	EUR 1176

Exosome precipitation from Plasma + Thrombin
EPStep-T	ImmunoStep	5 ml	EUR 403.2

Recombinant Human Exosome Component 9
7-05902	CHI Scientific	2µg	Ask for price

Recombinant Human Exosome Component 9
7-05903	CHI Scientific	10µg	Ask for price

Recombinant Human Exosome Component 9
7-05904	CHI Scientific	1mg	Ask for price

Recombinant Human Exosome Component 10
7-05905	CHI Scientific	5µg	Ask for price

Recombinant Human Exosome Component 10
7-05906	CHI Scientific	20µg	Ask for price

Recombinant Human Exosome Component 10
7-05907	CHI Scientific	1mg	Ask for price

Exosome Component 2 (EXOSC2) Antibody
20-abx172308	Abbexa	EUR 1028.40 EUR 526.80	1 mg 200 ug

Exosome Component 7 (EXOSC7) Antibody
20-abx124556	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Exosome Component 4 (EXOSC4) Antibody
20-abx124664	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Exosome Component 1 (EXOSC1) Antibody
20-abx125829	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Exosome Component 2 (EXOSC2) Antibody
20-abx125830	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Exosome Component 3 (EXOSC3) Antibody
20-abx125831	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Exosome Component 1 (EXOSC1) Antibody
20-abx112409	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Component 10 (EXOSC10) Antibody
20-abx112410	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Component 2 (EXOSC2) Antibody
20-abx112411	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Component 3 (EXOSC3) Antibody
20-abx112412	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Component 4 (EXOSC4) Antibody
20-abx112413	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Component 5 (EXOSC5) Antibody
20-abx112414	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Component 8 (EXOSC8) Antibody
20-abx112415	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Component 8 (EXOSC8) Antibody
20-abx003377	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Exosome Component 2 (EXOSC2) Antibody
20-abx003412	Abbexa	EUR 493.20 EUR 710.40	100 ul 200 ul

Exosome Component 4 (EXOSC4) Antibody
abx029390-400ul	Abbexa	400 ul	EUR 627.6

Exosome Component 4 (EXOSC4) Antibody
abx029390-80l	Abbexa	80 µl	EUR 343.2

Exosome Component 1 (EXOSC1) Antibody
abx030303-400ul	Abbexa	400 ul	EUR 627.6

Exosome Component 1 (EXOSC1) Antibody
abx030303-80l	Abbexa	80 µl	EUR 343.2

Exosome Component 2 (EXOSC2) Antibody
abx034983-400ul	Abbexa	400 ul	EUR 627.6

Exosome Component 2 (EXOSC2) Antibody
abx034983-80l	Abbexa	80 µl	EUR 343.2

Exosome Component 8 (EXOSC8) Antibody
abx031706-400ul	Abbexa	400 ul	EUR 627.6

Exosome Component 8 (EXOSC8) Antibody
abx031706-80l	Abbexa	80 µl	EUR 343.2

Exosome Component 1 (EXOSC1) Antibody
abx232898-100ug	Abbexa	100 ug	EUR 577.2

Exosome Component 10 (EXOSC10) Antibody
abx232899-100ug	Abbexa	100 ug	EUR 661.2

Exosome Component 10 (EXOSC10) Antibody
abx232900-100ug	Abbexa	100 ug	EUR 610.8

Exosome Component 2 (EXOSC2) Antibody
abx232901-100ug	Abbexa	100 ug	EUR 577.2

Exosome Component 2 (EXOSC2) Antibody
abx232902-100ug	Abbexa	100 ug	EUR 661.2

Exosome Component 3 (EXOSC3) Antibody
abx232903-100ug	Abbexa	100 ug	EUR 577.2

Exosome Component 4 (EXOSC4) Antibody
abx232904-100ug	Abbexa	100 ug	EUR 577.2

Exosome Component 5 (EXOSC5) Antibody
abx232905-100ug	Abbexa	100 ug	EUR 610.8

Exosome Component 7 (EXOSC7) Antibody
abx232906-100ug	Abbexa	100 ug	EUR 661.2

Exosome Component 8 (EXOSC8) Antibody
abx232907-100ug	Abbexa	100 ug	EUR 577.2

Exosome Component 9 (EXOSC9) Antibody
abx232908-100ug	Abbexa	100 ug	EUR 661.2

Exosome Component 10 (EXOSC10) Antibody
20-abx334343	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 1 (EXOSC1) Antibody
20-abx301763	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 5 (EXOSC5) Antibody
20-abx302857	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 3 (EXOSC3) Antibody
20-abx312069	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 8 (EXOSC8) Antibody
20-abx318649	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 2 (EXOSC2) Antibody
20-abx176346	Abbexa	EUR 510.00 EUR 159.60 EUR 1446.00 EUR 693.60 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

Exo-Check Exosome Antibody Array
322-EXO-FBS-50A-1	Gentaur Genprice	100 µg	EUR 469.2

Exo-Check Exosome Antibody Array
EXORAY200B-4	SBI	4 arrays	EUR 480

Exo-Check Exosome Antibody Array
EXORAY210B-8	SBI	8 arrays	EUR 910

ExoStd? Plasma Fluorescent Exosome Standard
M1073-100	Biovision	each	EUR 907.2

ExoStd? Serum Fluorescent Exosome Standard
M1074-100	Biovision	each	EUR 907.2

ExoStd? Urine Fluorescent Exosome Standard
M1075-100	Biovision	each	EUR 907.2

ExoStd? Saliva Fluorescent Exosome Standard
M1076-100	Biovision	each	EUR 907.2

ExoStd? COLO1 Fluorescent Exosome Standard
M1077-100	Biovision	each	EUR 907.2

ExoStd? MM1 Fluorescent Exosome Standard
M1078-100	Biovision	each	EUR 907.2

ExoStd? BLCL21 Fluorescent Exosome Standard
M1079-100	Biovision	each	EUR 907.2

ExoStd? HCT116 Fluorescent Exosome Standard
M1083-100	Biovision	each	EUR 907.2

ExoStd? PC3 Fluorescent Exosome Standard
M1086-100	Biovision	each	EUR 907.2

ExoStd? DAUD1 Fluorescent Exosome Standard
M1088-100	Biovision	each	EUR 907.2

ExoStd? A549 Fluorescent Exosome Standard
M1089-100	Biovision	each	EUR 907.2

ExoStd? B16F10 Fluorescent Exosome Standard
M1159-100	Biovision	each	EUR 927.6

E. coli 5S RNA (Helix 89 RNA), RNA Aptamer, unlabeled
AR-227-U	Alpha Diagnostics	Custom	Ask for price

RNA isolater Total RNA Extraction Reagent
R401-01	Vazyme	100 ml	EUR 159.6

RNA Kit
20-abx098089	Abbexa	EUR 126.00 EUR 410.40	2 rxns 50 rxns

RNA Beads
20-abx298002	Abbexa	EUR 260.40 EUR 477.60 EUR 1663.20	1 ml 5 ml 60 ml

MicroRNA scramble in CD511 - Virus
PMIRH000VA-1	SBI	1x10^6 IFUs	EUR 937.2

MicroRNA Precursor Pooled Plasmid Library
PMIRHPLPA-1	SBI	1 aliquot plasmid DNA	EUR 60

Stem Cell MicroRNA Profiling Panel
RA620A-1	SBI	10 profiles	EUR 1406.4

SanPrep Column microRNA Miniprep Kit
SK8811	Bio Basic	50prep	EUR 151.32

Exosome ELISA Complete Kit (CD81 detection)
EXOEL-CD81A-1	SBI	96 reactions	EUR 956.4

ExoQuick exosome precipitation solution (20 ml)
EXOQ20A-1	SBI	20 ml	EUR 1414.8

ExoQuick exosome precipitation solution (5 ml)
EXOQ5A-1	SBI	5 ml	EUR 480

Exosome precipitation from Plasma and Serum
EPStep-PS	ImmunoStep	5 ml	EUR 356.4

Exosome Complex Exonuclease DIS3 (DIS3) Antibody
20-abx123135	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Exosome Complex Exonuclease DIS3 (DIS3) Antibody
20-abx112095	Abbexa	EUR 878.40 EUR 477.60	150 ul 50 ul

Exosome Complex Exonuclease DIS3 (DIS3) Antibody
abx232394-100ug	Abbexa	100 ug	EUR 577.2

Exosome complex exonuclease DIS3 (DIS3) Antibody
20-abx334010	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 10 (EXOSC10) Antibody (HRP)
20-abx335640	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 10 (EXOSC10) Antibody (FITC)
20-abx335641	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 10 (EXOSC10) Antibody (Biotin)
20-abx335642	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Human Exosome Component 2 (EXOSC2) Protein
20-abx653328	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Exosome Component 5 (EXOSC5) Antibody (HRP)
20-abx311411	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 5 (EXOSC5) Antibody (FITC)
20-abx311412	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 5 (EXOSC5) Antibody (Biotin)
20-abx311413	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 3 (EXOSC3) Antibody (HRP)
20-abx312070	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 3 (EXOSC3) Antibody (FITC)
20-abx312071	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 3 (EXOSC3) Antibody (Biotin)
20-abx312072	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 1 (EXOSC1) Antibody (HRP)
20-abx312486	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 1 (EXOSC1) Antibody (FITC)
20-abx312487	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Exosome Component 1 (EXOSC1) Antibody (Biotin)
20-abx312488	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

The analyzed knowledge on the contamination and antimicrobial resistance patterns mixed with molecular typing may be helpful to derive threat administration of antimicrobial-resistant enterococci in meals.