The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide-Doxorubicin Binding to DNA

Matrix metalloproteinases (MMPs) are extracellular matrix degradation elements, selling most cancers development. Therefore, they might present an enzyme-assisted supply of doxorubicin (DOX) in most cancers remedy. Within the present research, the intercalation technique of DOX and tetrapeptide-DOX, the product of the MMPs’ cleavage of carrier-linked DOX, into dsDNA was investigated utilizing stationary and time-resolved fluorescence spectroscopy, UV-Vis spectrophotometry and isothermal titration calorimetry (ITC).

The molecular dynamics (MD) simulations on the identical tetrapeptide-DOX^…DNA and DOX^…DNA methods have been additionally carried out. The undertaken research point out that DOX and tetrapeptide-DOX can successfully bond with dsDNA via the intercalation mode; nonetheless, tetrapeptide-DOX kinds much less secure complexes than free DOX. Furthermore, the obtained outcomes show that the variations in DNA affinity of each types of DOX may be attributed to completely different intercalation modes.

Tetrapeptide-DOX exhibits a choice to intercalate into DNA via the main groove, whereas DOX does it via the minor one. In abstract, we are able to conclude that the tetrapeptide-DOX intercalation to DNA is critical and that even the dearth of non-specific proteases releasing DOX from the tetrapeptide conjugate, the presence of which is usually recommended by the literature for the environment friendly launch of DOX, mustn’t stop the cytostatic motion of the anthracycline.

Atmospheric strain photoionization versus electrospray for the dereplication of extremely conjugated pure merchandise utilizing molecular networks

Pure merchandise are sources of inspiration and reservoir of excessive priceless molecules. Not too long ago, analytical instruments based mostly on liquid chromatography coupled to tandem mass spectrometry to generate molecular community grew to become extensively employed for dereplication. This technique tremendously accelerates the identification of identified and structural speculation of unknown.

Regardless of the provision of various ionization sources, alternate options to classical electrospray ionization (ESI), comparable to atmospheric strain chemical ionization (APCI) or photoionization (APPI), have been uncared for. Specifically, APPI has been described for its ionization effectivity on non-polar molecules bearing no acid or primary teams. For that purpose, we investigated APPI potential to generate molecular community and evaluate it to ESI on a number of standards which are technology of ion species, sensitivity and signal-to-noise ratio (SNR) for various extracts wealthy in extremely conjugated pure merchandise.

We first optimized APPI experimental circumstances on crude extract from a fungus, Penicillium sclerotiorum, producing polyketones belonging to the azaphilone household. Then we in contrast APPI and ESI on completely different fractions of the fungus and on two plant extracts, French Guyanese Swartzia panacoco (Aubl.) R.S. Cowan (arial components) and Indian Cassia auriculata L. (leaves) containing phenolic compounds, comparable to flavonoids. Whereas ESI generated extra ion species and displayed a greater sensitivity, APPI generated solely protonated adduct and higher SNR. Evaluating ESI and APPI generated species on molecular community reveal that each methods overlap for almost all of protonated ions.

Cronobacter spp. remoted from aquatic merchandise in China: Incidence, antibiotic resistance, molecular attribute and CRISPR variety

Cronobacter species (Cronobacter spp.) are necessary foodborne pathogens that may infect and trigger severe life-threatening ailments in infants and immunocompromised aged. This research aimed to accumulate knowledge on Cronobacter spp. contamination of aquatic merchandise in China from 2011 to 2016. In whole, 800 aquatic merchandise have been examined, and the general contamination price for Cronobacter spp. was 3.9% (31/800). The common contamination stage of the constructive samples was 2.05 MPN/g. 4 species and 9 serotypes have been recognized amongst 33 isolates, of which the C. sakazakii serogroup O1 (n = 9) was the first serotype.

The vast majority of Cronobacter spp. strains harbored highest resistance in opposition to cephalothin (84.8%), adopted by tetracycline (6.1%), trimethoprim/sulfameth-oxazole (3.0%) and chloramphenicol (3.0%). Two isolates have been resistant to a few antibiotics. In whole, 26 sequence sorts and 33 CRISPR sorts (together with 6 new STs and 26 new CTs) have been recognized, which signifies the extraordinarily excessive variety of Cronobacter spp. in aquatic merchandise. Pathogenic C. sakazakii ST4, ST1, and C. malonaticus ST7 have been additionally noticed.

Total, this large-scale research revealed the comparatively low prevalence and excessive genetic variety of Cronobacter spp. in aquatic merchandise in China, and the findings present priceless data that may information the institution of efficient measures for the management and precaution of Cronobacter spp. in aquatic merchandise throughout manufacturing processes.

Prevalence, Antimicrobial Resistance and Molecular Range of Enterococcus faecium in Processed Pork Meat Merchandise in Korea

As a result of Enterococcus faecium is a crucial nosocomial pathogen and sentinel organism for monitoring antimicrobial resistance, data on the contamination and antimicrobial resistance patterns of E. faecium in meals are important to public well being and meals security.

We analyzed the incidence of E. faecium in retail pork meat merchandise (n = 124), and antimicrobial resistance of 30 E. faecium isolates have been examined in opposition to 14 antimicrobials utilizing the broth dilution check and disc diffusion check. Rep-PCR-based molecular variety was additionally analyzed utilizing Deviersilab. The very best contamination of enterococci was noticed for minced pork meat however many of the E. faecium was remoted from meatball-type frozen pork meat merchandise (FP).

Incidences of antimicrobial-resistant E. faecium in opposition to erythromycin, clindamycin and nitrofurantoin have been 80%, 50% and 20%, respectively. No vancomycin-resistant enterococci have been analyzed. Rep-PCR confirmed distinctive clusters with a similarity ≥ 98%, consisting of 18 E. faecium isolates from FP manufactured in seven corporations.

SeraMir Exosome RNA Purification Column kit (20 exoRNA columns)
RA808A-1	SBI	20 preps	EUR 402
Category: MicroRNA Tools

SeraMir Exosome RNA Purification kit (5ml ExoQuick and 20 exoRNA columns)
RA806A-1	SBI	20 preps	EUR 554
Category: MicroRNA Tools

Psoriasis Exosome RNA
P241-PS	101Bio	NULL	EUR 0

SeraMir Exosome RNA Purification kit (10ml ExoQuick-TC and 10 exoRNA columns) 10 preps
RA806TC-1	SBI	10 preps	EUR 554
Category: MicroRNA Tools

Normal human exosome RNA
P240	101Bio	NULL	EUR 0

Leukemia - ALL Exosome RNA
P241-ALL	101Bio	NULL	EUR 0

Leukemia - AML Exosome RNA
P241-AML	101Bio	NULL	EUR 0

Bladder Cancer Exosome RNA
P241-BL	101Bio	NULL	EUR 0

Breast Cancer Exosome RNA
P241-BR	101Bio	NULL	EUR 0

Leukemia - CLL Exosome RNA
P241-CLL	101Bio	NULL	EUR 0

Leukemia - CML Exosome RNA
P241-CML	101Bio	NULL	EUR 0

Colorectal Cancer Exosome RNA
P241-CO	101Bio	NULL	EUR 0

Crohn's Disease Exosome RNA
P241-CR	101Bio	NULL	EUR 0

Kidney Cancer Exosome RNA
P241-KN	101Bio	NULL	EUR 0

Lung Cancer Exosome RNA
P241-LG	101Bio	NULL	EUR 0

Liver Cancer Exosome RNA
P241-LV	101Bio	NULL	EUR 0

Nasopharyngeal Cancer Exosome RNA
P241-NA	101Bio	NULL	EUR 0

Prostate Cancer Exosome RNA
P241-PR	101Bio	NULL	EUR 0

Rheumatoid Arthritis Exosome RNA
P241-RA	101Bio	NULL	EUR 0

Thyroid Cancer Exosome RNA
P241-TH	101Bio	NULL	EUR 0

SeraMir Exosome RNA Amplification kit from Media and Urine (10ml ExoQuick-TC and 10 exoRNA columns)
RA800TC-1	SBI	10 reactions	EUR 659
Category: MicroRNA Tools

Green RNA Lysis Kit 50
GREENE1-RNA	Next Advance	50pack	EUR 180
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RNA Lysis Kit 250
GREENE5-RNA	Next Advance	250pack	EUR 571
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Navy RNA Lysis Kit 50
NAVYE1-RNA	Next Advance	50pack	EUR 198
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RNA Lysis Kit 250
NAVYE5-RNA	Next Advance	250pack	EUR 651
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Pink RNA Lysis Kit 50
PINKE1-RNA	Next Advance	50pack	EUR 178
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 250
PINKE5-RNA	Next Advance	250pack	EUR 561
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 50
REDE1-RNA	Next Advance	50pack	EUR 192
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 250
REDE5-RNA	Next Advance	250pack	EUR 622
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 50
YELLOWE1-RNA	Next Advance	50pack	EUR 192
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 250
YELLOWE5-RNA	Next Advance	250pack	EUR 624
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

LiqBiopsy Tumor Exosome RNA Kit
K1254-24	Biovision		EUR 1110

Diabetes (Type 1) Exosome RNA
P241-DB1	101Bio	NULL	EUR 0

Diabetes (Type 2) Exosome RNA
P241-DB2	101Bio	NULL	EUR 0

Leukemia - Hairy Cell Exosome RNA
P241-HC	101Bio	NULL	EUR 0

Leukemia - Multiple Myeloma Exosome RNA
P241-MM	101Bio	NULL	EUR 0

Melanoma (skin cancer) Exosome RNA
P241-MN	101Bio	NULL	EUR 0

Non-Hodgkin lymphoma Exosome RNA
P241-NH	101Bio	NULL	EUR 0

Systemic Lupus Erythematosus Exosome RNA
P241-SL	101Bio	NULL	EUR 0

Uterine Cervical Cancer Exosome RNA
P241-UC	101Bio	NULL	EUR 0

Uterine Corpus Cancer Exosome RNA
P241-UT	101Bio	NULL	EUR 0

Exosome Isolation kit (for serum & plasma -Exosome-RNA-NGS)
P101NGS	101Bio	NULL	EUR 0

5E GREEN RNA Lysis Kit 100
GREEN5E100-RNA	Next Advance	100pack	EUR 386
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

5E GREEN RNA Lysis Kit 20
GREEN5E20-RNA	Next Advance	20pack	EUR 138
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 50
GREENR1-RNA	Next Advance	50pack	EUR 184
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 250
GREENR5-RNA	Next Advance	250pack	EUR 587
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

5E Navy RNA Lysis Kit 100
NAVY5E100-RNA	Next Advance	100pack	EUR 453
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

5E Navy RNA Lysis Kit 20
NAVY5E20-RNA	Next Advance	20pack	EUR 153
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 50
NAVYR1-RNA	Next Advance	50pack	EUR 202
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 250
NAVYR5-RNA	Next Advance	250pack	EUR 666
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

5E PINK RNA Lysis Kit 100
PINK5E100-RNA	Next Advance	100pack	EUR 380
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E PINK RNA Lysis Kit 20
PINK5E20-RNA	Next Advance	20pack	EUR 136
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 50
PINKR1-RNA	Next Advance	50pack	EUR 181
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 250
PINKR5-RNA	Next Advance	250pack	EUR 576
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 100
RED5E100-RNA	Next Advance	100pack	EUR 429
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 20
RED5E20-RNA	Next Advance	20pack	EUR 148
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 50
REDR1-RNA	Next Advance	50pack	EUR 195
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 250
REDR5-RNA	Next Advance	250pack	EUR 638
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 50
YELLOWR1-RNA	Next Advance	50pack	EUR 199
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 250
YELLOWR5-RNA	Next Advance	250pack	EUR 656
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

SeraMir Control spike-in Small RNA and qPCR assay
RA805A-1	SBI	100 assays	EUR 235
Category: MicroRNA Tools

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA810A-1 components)
RA820A-1	SBI	20 profiles	EUR 1297
Category: MicroRNA Tools

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA812A-1 components)
RA822A-1	SBI	20 profiles	EUR 1297
Category: MicroRNA Tools

Exosome RNA Helicase MTR4 (MTR4) Antibody
abx149899-100ug	Abbexa	100 ug	EUR 439
Shipped within 5-10 working days.

ExoQuick Exosome RNA Column Purification kit
EQ808A-1	SBI	20 preps	EUR 402

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA811A-1 components) 20 profiles
RA821A-1	SBI	20 profiles	EUR 1297
Category: MicroRNA Tools

Exosome RNA Helicase MTR4 (MTR4/SKIV2L2) Antibody
20-abx004268	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA820TC-1	SBI	20 profiles	EUR 1618
Category: MicroRNA Tools

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA821TC-1	SBI	20 profiles	EUR 1618
Category: MicroRNA Tools

Exosome (Pre-isolated) RNA Extraction kit Note! This kit doesn't contain the conponents for exosome enrichment.
EIRK-01	Creative Biolabs	50 reactions	EUR 2817
Description: A RNA Extraction kit that is ideal for total RNA (miRNA+mRNAs) extraction from pre-isolated exosomes.

Total Exosome RNA Extraction Kit (Biological Fluids/Culture Media Supplement)
EIRK-03	Creative Biolabs	20 reactions	EUR 2817
Description: This product is a useful tool for the isolation and efficient total RNA (miRNA and mRNAs) extraction from the total exosome population from human biofluids or cell culture media.

Psoriasis Exosome
P141-PS	101Bio	NULL	EUR 0

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800TC-1 with 50ml ExoQuick-TC, RA805A-1 and RA812A-1 components)
RA822TC-1	SBI	20 profiles	EUR 1618
Category: MicroRNA Tools

SeraMir 3'-Universal Primer (10,000 qPCR reactions)
RA800P-3	SBI	10,000 reactions	EUR 178
Category: MicroRNA Tools

ExoQuick Exosome Isolation and RNA Purification kit (for Serum and Plasma)
EQ806A-1	SBI	20 preps	EUR 554

ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media)
EQ806TC-1	SBI	10 preps	EUR 554

TumorExoRNA? Tumor-derived exosome immunocapture and RNA extraction kit (10 reactions)
K1221-10	Biovision		EUR 827

TumorExoRNA? Tumor-derived exosome immunocapture and RNA extraction kit (20 reactions)
K1221-20	Biovision		EUR 1219

Lyophilized Exosome Standards
ExoA375	ImmunoStep	100 μg	EUR 303.5

Lyophilized Exosome Standards
ExoHT29	ImmunoStep	100 μg	EUR 303.5

Lyophilized Exosome Standards
ExoMCF7	ImmunoStep	100 μg	EUR 303.5

Lyophilized Exosome Standards
ExoPC3	ImmunoStep	100 μg	EUR 303.5

Lyophilized Exosome Standards
ExoPLASMA	ImmunoStep	100 μg	EUR 303.5

Lyophilized Exosome Standards
ExoUrine	ImmunoStep	100 μg	EUR 303.5

Exosome precipitation Solution
EPStep	ImmunoStep	12 ml	EUR 277.5

Leukemia - ALL Exosome
P141-ALL	101Bio	NULL	EUR 0

Leukemia - AML Exosome
P141-AML	101Bio	NULL	EUR 0

Bladder Cancer Exosome
P141-BL	101Bio	NULL	EUR 0

Breast Cancer Exosome
P141-BR	101Bio	NULL	EUR 0

Leukemia - CLL Exosome
P141-CLL	101Bio	NULL	EUR 0

Leukemia - CML Exosome
P141-CML	101Bio	NULL	EUR 0

Colorectal Cancer Exosome
P141-CO	101Bio	NULL	EUR 0

Crohn's Disease Exosome
P141-CR	101Bio	NULL	EUR 0

Kidney Cancer Exosome
P141-KN	101Bio	NULL	EUR 0

Lung Cancer Exosome
P141-LG	101Bio	NULL	EUR 0

Liver Cancer Exosome
P141-LV	101Bio	NULL	EUR 0

Nasopharyngeal Cancer Exosome
P141-NA	101Bio	NULL	EUR 0

Prostate Cancer Exosome
P141-PR	101Bio	NULL	EUR 0

Rheumatoid Arthritis Exosome
P141-RA	101Bio	NULL	EUR 0

Thyroid Cancer Exosome
P141-TH	101Bio	NULL	EUR 0

Exosome Component 5 Protein
20-abx260873	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 25 ug 5 ug
Shipped within 5-10 working days.

Exosome Component 7 Protein
20-abx261347	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Exosome Component 10 Protein
20-abx261805	Abbexa	EUR 4365.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Exosome Component 4 Protein
20-abx261954	Abbexa	EUR 4490.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug
Shipped within 5-10 working days.

Exosome Component 9 Protein
20-abx262123	Abbexa	EUR 328.00 EUR 5089.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

Exosome Component 3 Protein
20-abx263422	Abbexa	EUR 230.00 EUR 1609.00 EUR 328.00	1 µg 50 ug 5 ug
Shipped within 5-10 working days.

Exosome Component 1 Protein
20-abx263423	Abbexa	EUR 1609.00 EUR 328.00 EUR 230.00	100 ug 10 ug 2 µg
Shipped within 5-10 working days.

Exosome Component 8 Protein
20-abx262850	Abbexa	EUR 328.00 EUR 6397.00 EUR 230.00	10 ug 1 mg 2 µg
Shipped within 5-10 working days.

EXOCET Exosome Quantitation Kit
EXOCET96A-1	SBI	96 reactions	EUR 521
Category: Exosomes

FluoroCet Exosome Quantitation Kit
FCET96A-1	SBI	96 reactions	EUR 726
Category: Exosomes

Fluorescent Exosome Standard (Urine )
ESF-15	Creative Biolabs	100 µg	EUR 1723
Description: Fluorescent exosomes are labeled with green dye, which offer a stable fluorescent labeling.

Exosome-TEM-easy Kit
P130	101Bio	NULL	EUR 0

Diabetes (Type 1) Exosome
P141-DB1	101Bio	NULL	EUR 0

Diabetes (Type 2) Exosome
P141-DB2	101Bio	NULL	EUR 0

Leukemia - Hairy Cell Exosome
P141-HC	101Bio	NULL	EUR 0

Leukemia - Multiple Myeloma Exosome
P141-MM	101Bio	NULL	EUR 0

Melanoma (skin cancer) Exosome
P141-MN	101Bio	NULL	EUR 0

Non-Hodgkin lymphoma Exosome
P141-NH	101Bio	NULL	EUR 0

Systemic Lupus Erythematosus Exosome
P141-SL	101Bio	NULL	EUR 0

Uterine Cervical Cancer Exosome
P141-UC	101Bio	NULL	EUR 0

Uterine Corpus Cancer Exosome
P141-UT	101Bio	NULL	EUR 0

TotalExoRNA? Overall exosome immunocapture and RNA extraction kit (Biological Fluids/Cell Media, 20 reactions)
K1220-20	Biovision		EUR 1219

MicroRNA Isolation Kit
KS341025	Biochain	1 kit	EUR 256
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

ExoFectin Plasmid DNA-into-Exosome Kit (DNA transfection kit for exosome)
P402	101Bio	NULL	EUR 0

Glass Beads 0.1mm RNase Free
GB01-RNA	Next Advance	1pack	EUR 96
Description: Glass beads. 0.1mm. 4mL. RNase free.

Glass Beads 0.5mm RNase Free
GB05-RNA	Next Advance	1pack	EUR 96
Description: Glass beads. 0.5mm. 4mL. RNase free.

Measuring Spoon 100 RNase Free
MSP01-RNA	Next Advance	10pack	EUR 132
Description: 100uL (0.1mL) measuring spoon. Ideal for aliquoting beads into tubes. RNase free.

Measuring Spoon 500 RNase Free
MSP05-RNA	Next Advance	10pack	EUR 136
Description: 500uL (0.5mL) measuring spoon. Ideal for aliquoting beads into tubes. RNase free.

Orange Lysis Kit 50
ORANGEE1-RNA	Next Advance	50pack	EUR 165
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange Lysis Kit 250
ORANGEE5-RNA	Next Advance	250pack	EUR 537
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 50
ORANGER1-RNA	Next Advance	50pack	EUR 169
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 250
ORANGER5-RNA	Next Advance	250pack	EUR 554
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Stainless Steel Beads 0.2mm RNase Free
SSB02-RNA	Next Advance	1pack	EUR 121
Description: Stainless steel beads. 0.2mm. 4mL. RNase free.

Stainless Steel Beads 0.5mm RNase Free
SSB05-RNA	Next Advance	1pack	EUR 121
Description: Stainless steel beads. 0.5mm. 4mL. RNase free.

Stainless Steel Beads 0.9 - 2.0mm blend RNase Free
SSB14B-RNA	Next Advance	1pack	EUR 128
Description: Stainless steel beads. 0.9 - 2.0mm. 4mL. RNase free.

Stainless Steel Beads 1.6mm RNase Free
SSB16-RNA	Next Advance	1pack	EUR 128
Description: Stainless steel beads. 1.6mm. 4mL. RNase free.

Stainless Steel Beads 3.2mm RNase Free
SSB32-RNA	Next Advance	1pack	EUR 177
Description: Stainless steel beads. 3.2mm. 10mL. RNase free.

Stainless Steel Beads 4.8mm RNase Free
SSB48-RNA	Next Advance	1pack	EUR 177
Description: Stainless steel beads. 4.8mm. 10mL. RNase free.

Stainless Steel Beads 6.0mm RNase Free
SSB60-RNA	Next Advance	1pack	EUR 179
Description: Stainless steel beads. 6.0mm. 10mL. RNase free.

Stainless Steel UFO Beads 3.5mm RNase Free
SSUFO35-RNA	Next Advance	1pack	EUR 189
Description: Stainless steel UFO beads. 3.5mm. 10mL. RNase free.

Stainless Steel UFO Beads 5.6mm RNase Free
SSUFO56-RNA	Next Advance	1pack	EUR 190
Description: Stainless steel UFO beads. 5.6mm. 10mL. RNase free.

Zirconium Oxide Beads 0.15mm RNase Free
ZrOB015-RNA	Next Advance	1pack	EUR 106
Description: Fused Zirconium Oxide beads . 0.15mm. 4mL. RNase-free.

Zirconium Oxide Beads 0.5mm RNase Free
ZrOB05-RNA	Next Advance	1pack	EUR 106
Description: Zirconium Oxide beads . 0.5mm. 4mL. RNase-free.

Zirconium Oxide Beads 1.0mm RNase Free
ZrOB10-RNA	Next Advance	1pack	EUR 107
Description: Zirconium Oxide beads . 1.0mm. 4mL. RNase-free.

Zirconium Oxide Beads 2.0mm RNase Free
ZrOB20-RNA	Next Advance	1pack	EUR 107
Description: Zirconium Oxide beads . 2.0mm. 4mL. RNase-free.

Exosome isolation Solution - Serum/ Plasma (easy version of P101, 95% pure exosome)
P101EZ	101Bio	NULL	EUR 0

Recombinant Human Exosome Component 9
7-05902	CHI Scientific	2µg	Ask for price

Recombinant Human Exosome Component 9
7-05903	CHI Scientific	10µg	Ask for price

Recombinant Human Exosome Component 9
7-05904	CHI Scientific	1mg	Ask for price

Recombinant Human Exosome Component 10
7-05905	CHI Scientific	5µg	Ask for price

Recombinant Human Exosome Component 10
7-05906	CHI Scientific	20µg	Ask for price

Recombinant Human Exosome Component 10
7-05907	CHI Scientific	1mg	Ask for price

Exosome Component 8 (EXOSC8) Antibody
20-abx003377	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 2 (EXOSC2) Antibody
20-abx003412	Abbexa	EUR 411.00 EUR 592.00	100 ul 200 ul
Shipped within 5-10 working days.

Exosome Component 2 (EXOSC2) Antibody
20-abx176346	Abbexa	EUR 425.00 EUR 133.00 EUR 1205.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug
Shipped within 5-12 working days.

Exosome Component 1 (EXOSC1) Antibody
20-abx112409	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 10 (EXOSC10) Antibody
20-abx112410	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 2 (EXOSC2) Antibody
20-abx112411	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 3 (EXOSC3) Antibody
20-abx112412	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 4 (EXOSC4) Antibody
20-abx112413	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 5 (EXOSC5) Antibody
20-abx112414	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 8 (EXOSC8) Antibody
20-abx112415	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 7 (EXOSC7) Antibody
20-abx124556	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 4 (EXOSC4) Antibody
20-abx124664	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 1 (EXOSC1) Antibody
20-abx125829	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 2 (EXOSC2) Antibody
20-abx125830	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 3 (EXOSC3) Antibody
20-abx125831	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

Exosome Component 2 (EXOSC2) Antibody
abx034983-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

Exosome Component 2 (EXOSC2) Antibody
abx034983-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

Exosome Component 2 (EXOSC2) Antibody
20-abx172308	Abbexa	EUR 857.00 EUR 439.00	1 mg 200 ug
Please enquire.

Exosome Component 8 (EXOSC8) Antibody
abx031706-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

Exosome Component 8 (EXOSC8) Antibody
abx031706-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

Exosome Component 4 (EXOSC4) Antibody
abx029390-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

Exosome Component 4 (EXOSC4) Antibody
abx029390-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

Exosome Component 1 (EXOSC1) Antibody
abx030303-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

Exosome Component 1 (EXOSC1) Antibody
abx030303-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

Exosome Component 8 (EXOSC8) Antibody
20-abx318649	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Exosome Component 10 (EXOSC10) Antibody
20-abx334343	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Exosome Component 1 (EXOSC1) Antibody
20-abx301763	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Exosome Component 3 (EXOSC3) Antibody
20-abx312069	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Exosome Component 5 (EXOSC5) Antibody
20-abx302857	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Exosome Component 1 (EXOSC1) Antibody
abx232898-100ug	Abbexa	100 ug	EUR 481
Shipped within 5-12 working days.

Exosome Component 10 (EXOSC10) Antibody
abx232899-100ug	Abbexa	100 ug	EUR 551
Shipped within 5-12 working days.

Exosome Component 10 (EXOSC10) Antibody
abx232900-100ug	Abbexa	100 ug	EUR 509
Shipped within 5-12 working days.

Exosome Component 2 (EXOSC2) Antibody
abx232901-100ug	Abbexa	100 ug	EUR 481
Shipped within 5-12 working days.

Exosome Component 2 (EXOSC2) Antibody
abx232902-100ug	Abbexa	100 ug	EUR 551
Shipped within 5-12 working days.

Exosome Component 3 (EXOSC3) Antibody
abx232903-100ug	Abbexa	100 ug	EUR 481
Shipped within 5-12 working days.

Exosome Component 4 (EXOSC4) Antibody
abx232904-100ug	Abbexa	100 ug	EUR 481
Shipped within 5-12 working days.

Exosome Component 5 (EXOSC5) Antibody
abx232905-100ug	Abbexa	100 ug	EUR 509
Shipped within 5-12 working days.

Exosome Component 7 (EXOSC7) Antibody
abx232906-100ug	Abbexa	100 ug	EUR 551
Shipped within 5-12 working days.

Exosome Component 8 (EXOSC8) Antibody
abx232907-100ug	Abbexa	100 ug	EUR 481
Shipped within 5-12 working days.

Exosome Component 9 (EXOSC9) Antibody
abx232908-100ug	Abbexa	100 ug	EUR 551
Shipped within 5-12 working days.

Exo-Fect Exosome Transfection Kit
EXFT10A-1	SBI	10 reactions	EUR 293
Category: Exosomes

Exo-Fect Exosome Transfection Kit
EXFT20A-1	SBI	20 reactions	EUR 489
Category: Exosomes

Exosome-depleted FBS Media Supplement
EXO-FBS-250A-1	SBI	250 ml	EUR 881
Category: Exosomes

Exosome-depleted FBS Media Supplement
EXO-FBS-50A-1	SBI	50 ml	EUR 241
Category: Exosomes

Exo-FITC Exosome FACS stain
EXOFLOW800A-1	SBI	20 reactions	EUR 241
Category: Exosomes

Exo-APC Exosome FACS stain
EXOFLOW810A-1	SBI	20 reactions	EUR 241
Category: Exosomes

Exo-Check Exosome Antibody Array
EXORAY200A-4	SBI	4 arrays	EUR 540

Exo-Check Exosome Antibody Array
EXORAY210A-8	SBI	8 arrays	EUR 980

Exosome precipitation from Plasma + Thrombin
EPStep-T	ImmunoStep	5 ml	EUR 336

The analyzed knowledge on the contamination and antimicrobial resistance patterns mixed with molecular typing may be helpful to derive threat administration of antimicrobial-resistant enterococci in meals.