Antibodies

Appropriate Antigen Concentrations and Timing of a Nasal Provocation Test

Purpose: We aimed to determine appropriate antigen concentrations and the right time to evaluate intranasal changes when performing a nasal provocation test (NPT). Also, we sought to analyze the diagnostic usefulness of individual nasal symptom and peak nasal inspiratory flow (PNIF). Materials and methods: We divided 46 patients into allergic rhinitis (AR) group (n=19) and a non-allergic …

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COVID-19: Viral Transport Medium (VTM) for Diagnosis

The success of diagnosis of SARS-CoV-2 (2019-nCoV) during the COVID-19 outbreak largely depends on the quality of the sample and the conditions under which the sample is transported and stored before being processed in the laboratory. Viral transport medium (VTM) allows the safe transfer of viruses, chlamydia and mycoplasma for further research, which includes conventional …

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Evaluating platelet activation related to the degradation products of biomaterials using molecular markers

Evaluating platelet activation related to the degradation products of biomaterials using molecular markers

Rising numbers of biodegradable medical gadgets could also be used within the circulatory system. The consequences of the launched degradation merchandise from these medical gadgets on the blood could also be gradual and cumulative. Once they attain vital ranges, they might trigger thrombosis and different problems. Because of this, you will need to consider the …

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The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide-Doxorubicin Binding to DNA

The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide-Doxorubicin Binding to DNA

Matrix metalloproteinases (MMPs) are extracellular matrix degradation elements, selling most cancers development. Therefore, they might present an enzyme-assisted supply of doxorubicin (DOX) in most cancers remedy. Within the present research, the intercalation technique of DOX and tetrapeptide-DOX, the product of the MMPs’ cleavage of carrier-linked DOX, into dsDNA was investigated utilizing stationary and time-resolved fluorescence …

The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide-Doxorubicin Binding to DNA Read More »

Protective actions of bioactive flavonoids chrysin and luteolin on the glyoxal induced formation of advanced glycation end products and aggregation of human serum albumin: In vitro and molecular docking analysis

Protective actions of bioactive flavonoids chrysin and luteolin on the glyoxal induced formation of advanced glycation end products and aggregation of human serum albumin: In vitro and molecular docking analysis

The post-translational modification of proteins by nonenzymatic glycation (NEG) and the buildup of AGEs are the 2 underlying elements related to the long-term pathogenesis in diabetes. Glyoxal (GO) is a reactive intermediate which has the power to switch proteins and generate AGEs at a quicker fee. Human serum albumin (HSA) being probably the most ample …

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Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

This research aimed to organize the sugar business for the attainable introduction of genetically modified (GM) sugarcane and derived retail sugar merchandise and to deal with a number of potential public considerations concerning the traits and security of those merchandise. GM sugarcane strains with built-in Cry1Ab and EPSPS overseas genes have been used for GM sugar manufacturing. Conventional PCR, …

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Molecular assays for antimalarial drug resistance surveillance

Molecular assays for antimalarial drug resistance surveillance: A goal product profile. Antimalarial drug resistance is a significant constraint for malaria administration and elimination efforts. Artemisinin-based mixture therapy is now the mainstay for malaria treatment. Nonetheless, delayed parasite clearance following treatment with artemisinin derivatives has now unfold contained in the Greater Mekong Sub area and might emerge or unfold …

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