Evaluating platelet activation related to the degradation products of biomaterials using molecular markers

Evaluating platelet activation related to the degradation products of biomaterials using molecular markers

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Rising numbers of biodegradable medical gadgets could also be used within the circulatory system. The consequences of the launched degradation merchandise from these medical gadgets on the blood could also be gradual and cumulative. Once they attain vital ranges, they might trigger thrombosis and different problems. Because of this, you will need to consider the blood compatibility of degradation merchandise for high quality management and growth of those gadgets. Within the current research, we evaluated the degradation merchandise of 4 biodegradable supplies (collagen, polylactic acid, calcium phosphate ceramics, and magnesium) utilizing platelet activation molecular markers which can be related to thrombosis.

We discovered that the degradation merchandise activate platelets to a sure extent, and that the degradation merchandise produced throughout varied degradation time intervals activate platelets to various levels. This platelet activation happens through a number of mechanisms, most of that are related to the physicochemical properties of the degradation merchandise, together with ion focus, pH, molecular microstructure, and molecular weight. Our findings not solely present a clearer understanding of the consequences of degradation merchandise from blood-contacting biodegradable gadgets, but additionally present materials for screening of degradation habits in order to enhance high quality management for these gadgets.

Identification of potential anti-TMPRSS2 pure merchandise by means of homology modelling, digital screening and molecular dynamics simulation research

Latest outbreak of extreme acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a pandemic of COVID-19. The absence of a therapeutic drug and vaccine is inflicting extreme lack of life and financial system worldwide. SARS-CoV and SARS-CoV-2 make use of the host mobile serine protease TMPRSS2 for spike (S) protein priming for viral entry into host cells.

A possible method to cut back the preliminary website of SARS-CoV-2 an infection could also be to inhibit the exercise of TMPRSS2. Within the present research, the three-dimensional construction of TMPRSS2 was generated by homology modelling and subsequently validated with a variety of parameters. The structure-based digital screening of Selleckchem database was carried out by means of ‘Digital Work Stream’ (VSW) to search out out potential lead-like TMPRSS2 inhibitors. Camostat and bromhexine are identified TMPRSS2 inhibitor medication, therefore these have been used as management molecules all through the research.

Based mostly on higher dock rating, binding-free vitality and binding interactions in comparison with the management molecules, six molecules (Neohesperidin, Myricitrin, Quercitrin, Naringin, Icariin, and Ambroxol) have been discovered to be promising towards the TMPRSS2. Binding interactions evaluation revealed a variety of vital binding interactions with binding website amino residues of TMPRSS2.

Evaluating platelet activation related to the degradation products of biomaterials using molecular markers

The all-atoms molecular dynamics (MD) simulation research indicated that each one proposed molecules retain contained in the receptor in dynamic states. The binding vitality calculated from the MD simulation trajectories additionally favour the sturdy affinity of the molecules in direction of the TMPRSS2. Proposed molecules belong to the bioflavonoid class of phytochemicals and are reported to own antiviral exercise, our research signifies their potential potential for utility in COVID-19. Communicated by Ramaswamy H. Sarma.

Molecular characterization of Campylobacter spp. recovered from beef, rooster, lamb and pork merchandise at retail in Australia

Australian charges of campylobacteriosis are among the many highest in developed nations, but solely restricted work has been completed to characterize Campylobacter spp. in Australian retail merchandise. We carried out entire genome sequencing (WGS) on 331 C. coli and 285 C. jejuni from retail rooster meat, in addition to beef, rooster, lamb and pork offal (organs). Campylobacter isolates have been extremely numerous, with 113 sequence varieties (STs) together with 38 novel STs, recognized from 616 isolates. Genomic evaluation suggests very low ranges (2.3-15.3%) of resistance to aminoglycoside, beta-lactam, fluoroquinolone, macrolide and tetracycline antibiotics.

A majority (>90%) of isolates (52/56) possessing the fluoroquinolone resistance-associated T86I mutation within the gyrA gene belonged to ST860, ST2083 or ST7323. The 44 pork offal isolates have been extremely numerous, representing 33 STs (11 novel STs) and harboured genes related to resistance to aminoglycosides, lincosamides and macrolides not usually present in isolates from different sources.

Prevalence of multidrug resistant genotypes was very low (<5%), however ten-fold greater in C. coli than C. jejuni. This research highlights that Campylobacter spp. from retail merchandise in Australia are extremely genotypically numerous and vital variations in antimicrobial resistance exist between Campylobacter species and animal sources.

Molecular identification and efficiency analysis of untamed yeasts from totally different Ethiopian fermented merchandise

Several types of yeasts and lactic acid micro organism dominate in spontaneously fermented merchandise (meals, drinks, and condiments) which can be generally consumed in Ethiopia. The intention of this research was to determine environment friendly fermentative yeasts from fermented meals, fermented drinks, honey and molasses utilizing genotypic strategies. Out of the 70 samples examined, 180 distinct wild yeast isolates have been recovered. A complete of 23 isolates have been chosen for genomic evaluation primarily based on their foundation of biomass yield, fermentation capability, and leavening efficiency.

The nucleotide sequence evaluation of the inner transcribed spacer ITS-5.8S rDNA area revealed that the indigenous yeast isolates had shut relatedness to Saccharomyces cerevisiae, Candida humilis, Kazachstania bulderi, Pichia fermentans and Pichia kudriavzevii with higher than 97% nucleotide similarity.

E.coli DNA Amplification Kit in wells
D415W 1 kit (96 wells plate)
EUR 1303.2
Description: E.coli DNA Amplification Kit in wells by Cygnus Technologies is available in Europe via Gentaur.

GenomiPhi HY DNA Amplification Kit 25 rxns - EACH
25660022 EACH
EUR 757.35

1X Amplification Diluent
H1001-30 30ml
EUR 40
Description: TSA Reagent

1X Amplification Diluent
H1001-60 60ml
EUR 64
Description: TSA Reagent

GenomiPhi HY DNA Amplification Kit 1000 reactions - EACH
25660025 EACH
EUR 22175.1

illustra GenomiPhi V2 DNA Amplification Kit 100 rxns - EACH
25660031 EACH
EUR 606.15

Library Amplification SuperMix
abx098894-100l 100 µl
EUR 737.5

Library Amplification SuperMix
abx098894-200l 200 µl
EUR 1137.5

Library Amplification SuperMix
20-abx098894
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  • 1 ml
  • 5 ml

Single Cell Sequence Specific Amplification Kit
P621-01 200 rxn
EUR 435

illustra GenomiPhi V2 DNA Amplification Kit 25 rxns - EACH
25660030 EACH
EUR 224.1

illustra TempliPhi 100 Amplification Kit 100 rxns - EACH
25640010 EACH
EUR 305.1

illustra TempliPhi 500 Amplification Kit 500 rxns - EACH
25640050 EACH
EUR 1464.75

illustra GenomiPhi V2 DNA Amplification Kit 500 reactions - EACH
25660032 EACH
EUR 2949.75

96 WELL BARCODED H1-H12, CLEAR PCR FULL SKIRT PCR AMPLIFICATION MICRO PLATE
PCR-96-FS-C-PBC 10/pk
EUR 201.6
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Nunc Amplification Tape 96 - PK100
232702 PK100
EUR 257.85

DNA Amplification Kit with Taq DNA Polymerase, 100app
PL1202-K each Ask for price

MycoScreen Real-TM NEW Real Time Amplification kit
F23-48FRT 48
EUR 1220.8

VAHTS HiFi Amplification Mix for MGI
NM616-01 24 rxn
EUR 201.6

VAHTS HiFi Amplification Mix for MGI
NM616-02 96 rxn
EUR 363.6

Plasmid amplification and purification
S203 - Ask for price

Coxiella burnetii Real-TM Real Time Amplification kit
B85-50FRT 50
EUR 560.26

DNA Amplification Kit with Max Taq DNA Polymerase, 100app
PL2202-K each Ask for price

DNA Amplification Kit with Chromo Taq DNA Polymerase, 100app
PL1206-K each Ask for price

TruePrime Liquid Biopsy ctDNA Amplification Kit (25 reactions)
EP330025 each
EUR 1057.3

TruePrime apoptotic cell-free DNA amplification kit (5 Rxn)
EP340005 each
EUR 1139.05

TruePrime apoptotic cell-free DNA amplification kit (20 Rxn)
EP340020 each
EUR 3994.85

HiPer® Random Amplification of Polymorph
HTBM031-5PR 1 unit
EUR 82.29
Description: HiPer® Random Amplification of Polymorph

DNA Amplification Kit with Chromo Max Taq DNA Polymerase, 100app
PL2206-K each Ask for price

6 WELL BLUE PCR FULL SKIRT AMPLIFICATION PLATE.
PCR-96-FS-B 10/pk
EUR 211.2
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Tyramide Amplification Buffer Plus, 1000 reactions
22029-1 KT
EUR 492

Tyramide Amplification Buffer Plus, 250 reactions
22029-T -
EUR 127
Description: N/A

Tyramide Amplification Buffer Plus, 250 reactions
22029-T-1 KT
EUR 127

96 WELL CLEAR PCR HALF SKIRT AMPLIFICATION PLATE
PCR-96-HS-C 10/pk
EUR 190.8
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

VAHTS HiFi Universal Amplification Mix for MGI (SI)
NM618-00-6rxns 6 rxns
EUR 1.09

VAHTS HiFi Universal Amplification Mix for MGI (SI)
NM618-01 24 rxns
EUR 38.5

VAHTS HiFi Universal Amplification Mix for MGI (SI)
NM618-01-24rxns 24 rxns
EUR 39.87

VAHTS HiFi Universal Amplification Mix for MGI (SI)
NM618-02 96 rxns
EUR 134

VAHTS HiFi Universal Amplification Mix for MGI (SI)
NM618-02-96rxns 96 rxns
EUR 138.76

Ready-to-Use Tyramide Amplification Buffer, 1X
9-22027
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  • 25ML
  • 100ML
Description: N/A

Ready-to-Use Tyramide Amplification Buffer, 1X
22027-100mL-1 KT
EUR 472

Ready-to-Use Tyramide Amplification Buffer, 1X
22027-25mL-1 KT
EUR 118

Tyramide Amplification Kit with HRP Streptavidin and CF®543 Tyramide
33005-1 KT
EUR 564

Tyramide Amplification Kit with HRP Streptavidin and CF®568 Tyramide
33008-1 KT
EUR 564

Tyramide Amplification Kit with HRP Streptavidin and CF®594 Tyramide
33011-1 KT
EUR 564

Tyramide Amplification Kit with HRP Streptavidin and CF®488A Tyramide
33002-1 KT
EUR 564

Tyramide Amplification Kit with HRP Streptavidin and CF®640R Tyramide
33014-1 KT
EUR 564

Tyramide Amplification Kit with HRP Streptavidin and CF®680R Tyramide
33017-1 KT
EUR 564

VAHTS HiFi Universal Amplification Mix for Illumina
N618-00-6rxns 6 rxns
EUR 1.09

VAHTS HiFi Universal Amplification Mix for Illumina
N618-01 24 rxns
EUR 38.5

VAHTS HiFi Universal Amplification Mix for Illumina
N618-01-24rxns 24 rxns
EUR 39.87

VAHTS HiFi Universal Amplification Mix for Illumina
N618-02 96 rxns
EUR 134

VAHTS HiFi Universal Amplification Mix for Illumina
N618-02-96rxns 96 rxns
EUR 138.76

REMBRANDT® HER2 amplification FISH detection assay
C801K.5206 Kit Ask for price

REMBRANDT® HER2 amplification FISH detection assay
C801K.5206.05 Kit
EUR 501

REMBRANDT® HER2 amplification FISH detection assay
C801K.5206.10 Kit
EUR 927

REMBRANDT® TERC amplification FISH detection assay
C814K.2030.05 Kit
EUR 501

REMBRANDT® TERC amplification FISH detection assay
C814K.2030.10 Kit
EUR 927

REMBRANDT® SOX2 amplification FISH detection assay
C815K.2030.05 Kit
EUR 501

REMBRANDT® SOX2 amplification FISH detection assay
C815K.2030.10 Kit
EUR 927

REMBRANDT® EGFR amplification FISH detection assay
C816K.2030.05 Kit
EUR 501

REMBRANDT® EGFR amplification FISH detection assay
C816K.2030.10 Kit
EUR 927

REMBRANDT® MDM2 amplification FISH detection assay
C817K.2030.05 Kit
EUR 501

REMBRANDT® MDM2 amplification FISH detection assay
C817K.2030.10 Kit
EUR 927

Tyramide Amplification Kit with HRP Streptavidin and Biotin-XX Tyramide
33020-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Mouse and CF®543 Tyramide
33003-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Mouse and CF®568 Tyramide
33006-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Mouse and CF®594 Tyramide
33009-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Rabbit and CF®543 Tyramide
33004-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Rabbit and CF®568 Tyramide
33007-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Rabbit and CF®594 Tyramide
33010-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Mouse and CF®640R Tyramide
33012-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Mouse and CF®680R Tyramide
33015-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Mouse and CF®488A Tyramide
33000-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Rabbit and CF®488A Tyramide
33001-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Rabbit and CF®640R Tyramide
33013-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Rabbit and CF®680R Tyramide
33016-1 KT
EUR 564

Recombinant Adenovirus Amplification (1ml: 1x10E12 VPs/ml)
fAP-0007-1ml Service Ask for price

Recombinant Adenovirus Amplification (3ml: 1x10E12 VPs/ml)
fAP-0007-3ml Service Ask for price

Tyramide Amplification Kit with HRP Goat Anti-Mouse and Biotin-XX Tyramide
33018-1 KT
EUR 564

Tyramide Amplification Kit with HRP Goat Anti-Rabbit and Biotin-XX Tyramide
33019-1 KT
EUR 564

REMBRANDT® LSI 3q26.2/CEP3 amplification ISH detection assay
C814K.0199.05 Kit
EUR 501

REMBRANDT® LSI 3q26.2/CEP3 amplification ISH detection assay
C814K.0199.10 Kit
EUR 927

REMBRANDT® LSI 3q26.33/CEP3 amplification ISH detection assay
C815K.0199.05 Kit
EUR 501

REMBRANDT® LSI 3q26.33/CEP3 amplification ISH detection assay
C815K.0199.10 Kit
EUR 927

REMBRANDT® LSI 7p11.2/CEP7 amplification ISH detection assay
C816K.0199.05 Kit
EUR 501

REMBRANDT® LSI 7p11.2/CEP7 amplification ISH detection assay
C816K.0199.10 Kit
EUR 927

REMBRANDT® LSI 17q12/CEP17 amplification ISH detection assay
C801K.0199.05 Kit
EUR 501

REMBRANDT® LSI 17q12/CEP17 amplification ISH detection assay
C801K.0199.10 Kit
EUR 927

REMBRANDT® LSI 12q15/CEP12 amplification ISH detection assay
C817K.0199.05 Kit
EUR 501

REMBRANDT® LSI 12q15/CEP12 amplification ISH detection assay
C817K.0199.10 Kit
EUR 927

Ready-to-go(TM) Genomiphi(TM) V3 DNA Amplification Kit; Cytiva; 25-6601-96; sufficient for 96 reactions - PK96
GE25-6601-96 PK96
EUR 766.8

96 WELL RED PCR HALF SKIRT AMPLIFICATION PLATE WITH A SINGLE NOTCH
PCR-96M2-HS-R 10/pk
EUR 234
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Phanta UC Super-Fidelity DNA Polymerase for Library Amplification
P507-01 100 U
EUR 188.4

Phanta UC Super-Fidelity DNA Polymerase for Library Amplification
P507-02 500 U
EUR 408

96 WELL BLACK PCR HALF SKIRT AMPLIFICATION PLATE WITH A SINGLE NOTCH
PCR-96M2-HS-BK 10/pk
EUR 224.4
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR PCR HALF SKIRT AMPLIFICATION PLATE WITH A SINGLE NOTCH
PCR-96M2-HS-C 10/pk
EUR 200.4
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL YELLOW PCR HALF SKIRT AMPLIFICATION PLATE WITH A SINGLE NOTCH
PCR-96M2-HS-Y 10/pk
EUR 234
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

SeraMir Exosome RNA Amplification kit from Media and Urine (10ml ExoQuick-TC and 10 exoRNA columns)
RA800TC-1 10 reactions
EUR 595

96 WELL BARCODED H1-H12, CLEAR PCR HALF SKIRT AMPLIFICATION PLATE WITH A SINGLE NOTCH
PCR-96M2-HS-C-PBC 10/pk
EUR 272.4
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR PCR HALF SKIRT SINGLE BAR-CODED AMPLIFICATION PLATE WITH A SINGLE NOTCH.
PCR-96M2-HS-C-BC 10/pk
EUR 274.8
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

Sa2Res-SAMPLE TO RESULT Fully automated DNA/RNA extractor, PCR setup and qPCR amplification instrument
S2R-48 each Ask for price

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA810A-1 components)
RA820A-1 20 profiles
EUR 1220

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA812A-1 components)
RA822A-1 20 profiles
EUR 1220

Enhancing Wash Buffer for rinse/amplification of IHC-DAB & AEC stains and for fluorescence stains, 4-Liters; Ready-To-Use
NB301 4 Liters
EUR 385

Enhancing Wash Buffer for rinse/amplification of IHC-DAB & AEC stains and for fluorescence stains, 1-Liter of 5X Concentrate
NB301-5C 1 Liter of 5X
EUR 425

Enhancing Wash Buffer for rinse/amplification of IHC-DAB & AEC stains and for fluorescence stains, 1-Liter; Ready-To-Use
NB301S 1 Liter
EUR 185

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit (contains cat# RA800A-1, RA805A-1, RA811A-1 components) 20 profiles
RA821A-1 20 profiles
EUR 1220

Human Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA820TC-1 20 profiles
EUR 1533

Mouse Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800A-1, RA805A-1, RA810A-1 and EXOTC50A-1 components)
RA821TC-1 20 profiles
EUR 1533

Rat Complete SeraMir Exosome RNA Amplification and Profiling Kit for Media and Urine (contains cat# RA800TC-1 with 50ml ExoQuick-TC, RA805A-1 and RA812A-1 components)
RA822TC-1 20 profiles
EUR 1533

Direct qPCR ProbesMasterRobust real-time PCR master mix for amplification directly from blood, swabs or tissue, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service
M-PCR-396L 10 x 1,25 ml
EUR 1022
Description: Direct qPCR ProbesMasterRobust real-time PCR master mix for amplification directly from blood, swabs or tissue, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

Direct qPCR ProbesMasterRobust real-time PCR master mix for amplification directly from blood, swabs or tissue, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service
M-PCR-396S 2 x 1,25 ml
EUR 256
Description: Direct qPCR ProbesMasterRobust real-time PCR master mix for amplification directly from blood, swabs or tissue, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

Direct qPCR ProbesMaster highROXRobust real-time PCR master mix for amplification directly from blood, swabs or tissue with highROX, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service
M-PCR-397L 10 x 1,25 ml
EUR 1022
Description: Direct qPCR ProbesMaster highROXRobust real-time PCR master mix for amplification directly from blood, swabs or tissue with highROX, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

Direct qPCR ProbesMaster highROXRobust real-time PCR master mix for amplification directly from blood, swabs or tissue with highROX, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service
M-PCR-397S 2 x 1,25 ml
EUR 256
Description: Direct qPCR ProbesMaster highROXRobust real-time PCR master mix for amplification directly from blood, swabs or tissue with highROX, 2 x conc. master mix** shipped ice packs - must be shipped via overnight service

ELISA PLATE READER : MICRO READ 1000
1000 1 unit
EUR 2628

ELISA PLATE WASHER : MICRO WASH 1100
1100 1 unit
EUR 2403.6

ELISA PLATE SHAKER : MICRO SHAKE 1200
1200 1 unit
EUR 916.8

EZClick? Global RNA Synthesis Assay Kit (FACS/Microscopy), Red Fluorescence
K718-100 each
EUR 639.6

EZClick? Global RNA Synthesis Assay Kit (FACS/Microscopy), Red Fluorescence
K462-100 each
EUR 639.6

EZClick? Global Protein Synthesis Assay Kit (FACS/Microscopy), Red Fluorescence
K715-100 each
EUR 660

EZClick? Global Protein Synthesis Assay Kit (FACS/Microscopy), Green Fluorescence
K459-100 each
EUR 660

microRNA Purification Kit
21300 25 Preps
EUR 149.4

EZClick? Global Phospholipid Synthesis Assay Kit (FACS/Microscopy), Red Fluorescence
K717-100 each
EUR 614.4

MicroRNA-Isolation-Kit
KS341025 1 kit
EUR 208.6

Plant microRNA Purification Kit
54700 25 Preps
EUR 149.4

Urine microRNA Purification Kit
29000 25 Preps
EUR 167.4

Plant MicroRNA Purification Kit
10760135-1 25 Prep(s)
EUR 316.11

microRNA mimics
GC0092 5 nmol/2 OD
EUR 48.95

microRNA agomiR
GC0096 5 nmol/2 OD
EUR 87.45

microScript microRNA cDNA Synthesis Kit
54410 50 Reactions
EUR 219

microScript microRNA cDNA Synthesis Kit
54415 12 Reactions
EUR 53.4

Human MicroRNA-210 (miR-210) ELISA Kit
MBS3800168-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human MicroRNA-210 (miR-210) ELISA Kit
MBS3800168-48StripWells 48-Strip-Wells
EUR 550

Human MicroRNA-210 (miR-210) ELISA Kit
MBS3800168-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human MicroRNA-210 (miR-210) ELISA Kit
MBS3800168-96StripWells 96-Strip-Wells
EUR 765

Human microrna-21(mir-21) ELISA Kit
SL3405Hu 96 Tests
EUR 468

microRNA inhibitor
GC0093 10 nmol/2 OD
EUR 48.95

microRNA antagomiR
GC0097 10 nmol/2 OD
EUR 87.45

SanPrep Column microRNA Miniprep Kit
SK8811 50prep
EUR 151.32

microRNA-21-IN-2
HY-151516 10 mg
EUR 346.33
Description: microRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. microRNA-21-IN-2 can be used for the research of cancer[1].

microRNA-21-IN-3
HY-153534 1 mg
EUR 2056.31
Description: microRNA-21-IN-3 (compound 45) can specifically bind to the precursor of oncogenic and pro-inflammatory microRNA-21 with medium nanomolar affinity, reduce cancer cell proliferation and miR-21 levels, and can be used in antitumor research[1].

microRNA-21-IN-1
HY-146411 1 mg
EUR 2943.77
Description: microRNA-21-IN-1 (compound 7A) is an efficient microRNA inhibitor. microRNA-21-IN-1 has antiproliferative activity against Hela and HCT-116 cells with IC50s of 5.5 μM and 2.8 μM respectively, as well as promotes apoptosis of Hela cells. microRNA-21-IN-1 upregulates the expression of microRNA-21 downstream functional targets (PTEN, EGR1 and SLIT2). microRNA-21-IN-1 can be used for researching anticancer[1].

microRNA-21-IN-1
T63879-10mg 10mg Ask for price
Description: microRNA-21-IN-1

The research exhibits a excessive variety of indigenous wild yeasts in fermented merchandise and that potent strains had greater biomass yield, good fuel manufacturing and noteworthy leavening capability that signifies their inherent potential to be used within the baking trade.

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