Structure-activity relationship, molecular docking, and molecular dynamic studies of diterpenes from marine natural products with anti-HIV activity

HIV-1 an infection is a world epidemic whose therapy is proscribed majorly by viral resistance and opposed results. Pure merchandise from algae have been studied for a few years, together with antiviral, being an alternative choice to anti-HIV drug design. Because the isolation of pure merchandise could be a hurdle, molecular modeling is a vital software to check these compounds.

Herein, structure-activity relationship, molecular docking, and molecular dynamic research have been carried out to direct the research of ten marine pure merchandise with anti-HIV exercise. Within the structure-activity relationship, descriptors have been recognized associating the anti-HIV exercise of 5 diterpenes with potential motion on the reverse transcriptase allosteric web site.

These diterpenes have been evaluated by molecular docking, and it was recognized that solely dolabelladienetriol interacted within the allosteric web site. Molecular dynamics steered that the dolabelladienetriol would possibly intervene with the viral RNA binding to HIV-1 RT by inducing a conformational change of the enzyme. Additionally, in silico ADMET simulations predicts that the dolabelladienetriol current a excessive potential to be efficiently developed as a drug. Thus, making use of in silico approaches was potential to recommend potential anti-HIV compounds derived from marine pure merchandise. Communicated by Ramaswamy H. Sarma.

Molecular Genomic Options Related to in Vitro Response of the NCI-60 Most cancers Cell Line Panel to Pure Merchandise

Pure merchandise stay a major supply of anti-cancer chemotherapeutics. The seek for focused medicine for most cancers therapy consists of consideration of pure merchandise which can present new alternatives for anti-tumor cytotoxicity as single brokers or together remedy. We examined the affiliation of molecular genomic options within the well-characterized NCI-60 most cancers cell line panel with in vitro response to therapy with 1,302 small molecules which included pure merchandise, semi-synthetic pure product derivatives, and artificial compounds based mostly on a pure product pharmacophore from the Developmental Therapeutics Program of the US Nationwide Most cancers Institute’s database.

These compounds have been obtained from a wide range of plant, marine, and microbial species. Molecular info utilized for the evaluation included expression measures for 23,059 annotated transcripts, lncRNAs, and miRNAs, and information on protein-changing single nucleotide variants in 211 cancer-related genes. We discovered associations of expression of a number of genes together with SLFN11, CYP2J2, EPHX1, GPC1, ELF3, and MGMT concerned in DNA injury restore, NOTCH members of the family, ABC and SLC transporters, and each mutations in tyrosine kinases and BRAF V600E with NCI-60 responses to particular classes of pure merchandise. Hierarchical clustering recognized teams of pure merchandise which correlated with a particular mechanism of motion. Particularly, a number of pure product clusters have been related to SLFN11 gene expression, suggesting that potential motion of those compounds could contain DNA injury.

The associations between gene expression or genome alterations of functionally related genes with the response of most cancers cells to pure merchandise present new details about potential mechanisms of motion of those recognized clusters of compounds with doubtlessly comparable organic results. This info will help in future drug discovery and in design of latest focused most cancers chemotherapy brokers.

A New Strategy Based mostly on Glued Multi-Extremely Excessive Molecular Weight Polyethylene Types to Fabricate Bone Substitute Merchandise

Three forms of glue based mostly on thiol-ene response, polyvinyl alcohol (PVA)/cellulose, and phenol formaldehyde have been ready and utilized on modified ultra-high molecular weight polyethylene (UHMWPE) samples grafted by cellulose. Compared with unmodified UHMWPE samples, T-peel assessments on the modified and grafted UHMWPE movies confirmed a rise within the peel power values for the glues based mostly on thiol-ene response, PVA/cellulose, and phenol formaldehyde by 40, 29, and 41 instances, respectively. The utmost peel power worth of 0.62 Kg/cm was obtained for the glue based mostly on phenol formaldehyde.

Mechanical assessments for the cylindrical multi-UHMWPE kinds samples, fabricated from porous UHMWPE as a trabecular layer and an armored layer (cortical layer) that consists of bulk and UHMWPE movies, indicated an enchancment within the mechanical properties of those samples for all glue sorts, because of the UHMWPE movies existence and the rise within the variety of their layers.

The utmost compressive yield power and compressive modulus values for the armored layer (bulk and 6 layers of the UHMWPE movies utilizing the glue based mostly on thiol-ene response) have been 44.1 MPa (a rise of 17%) and 1130 MPa (a rise of 36%), respectively, compared with one armored layer of bulk UHMWPE. A hemocompatibility check carried out on these glues clarified that the modified UHMWPE grafted by cellulose with glues based mostly on PVA/cellulose and thiol-ene response have been categorized as biocompatible supplies. These multi-UHMWPE kinds composites may be thought of a promising improvement for joint reconstruction.

Plant Derived Pure Merchandise towards Pseudomonas aeruginosa and Staphylococcus aureus: Antibiofilm Exercise and Molecular Mechanisms

Micro organism are social organisms in a position to construct advanced buildings, resembling biofilms, which can be extremely organized surface-associated communities of microorganisms, encased inside a self- produced extracellular matrix. Biofilm is often related to many well being issues since its formation will increase resistance to antibiotics and antimicrobial brokers, as within the case of Pseudomonas aeruginosa and Staphylococcus aureus, two human pathogens inflicting main concern. P. aeruginosa is accountable for extreme nosocomial infections, essentially the most frequent of which is ventilator-associated pneumonia, whereas S. aureus causes a number of issues, like pores and skin infections, septic arthritis, and endocarditis, to call only a few.

Literature information recommend that pure merchandise from crops, micro organism, fungi, and marine organisms have confirmed to be efficient as anti-biofilm brokers, inhibiting the formation of the polymer matrix, suppressing cell adhesion and attachment, and reducing the virulence components’ manufacturing, thereby blocking the quorum sensing community.

Blank Calibration Particles
BCP-300-5	Spherotech	5 mL	EUR 237.6
Description: Blank Calibration ParticlesCalibration Particles are designed for the detmination of the flow cytometer's fluorescence threshold. It is important to determine if the autofluorescence level of a sample is above the fluorescence threshold of the instrument.

Blank Calibration Particles
BCP-32-5	Spherotech	5 mL	EUR 218.4
Description: Blank Calibration ParticlesCalibration Particles are designed for the detmination of the flow cytometer's fluorescence threshold. It is important to determine if the autofluorescence level of a sample is above the fluorescence threshold of the instrument.

Blank Calibration Particles
BCP-35-5	Spherotech	5 mL	EUR 218.4
Description: Blank Calibration ParticlesCalibration Particles are designed for the detmination of the flow cytometer's fluorescence threshold. It is important to determine if the autofluorescence level of a sample is above the fluorescence threshold of the instrument.

Blank Calibration Particles
BCP-50-5	Spherotech	5 mL	EUR 218.4
Description: Blank Calibration ParticlesCalibration Particles are designed for the detmination of the flow cytometer's fluorescence threshold. It is important to determine if the autofluorescence level of a sample is above the fluorescence threshold of the instrument.

Blank Calibration Particles
BCP-60-5	Spherotech	5 mL	EUR 218.4
Description: Blank Calibration ParticlesCalibration Particles are designed for the detmination of the flow cytometer's fluorescence threshold. It is important to determine if the autofluorescence level of a sample is above the fluorescence threshold of the instrument.

Blank Calibration Particles
BCP-70-5	Spherotech	5 mL	EUR 218.4
Description: Blank Calibration ParticlesCalibration Particles are designed for the detmination of the flow cytometer's fluorescence threshold. It is important to determine if the autofluorescence level of a sample is above the fluorescence threshold of the instrument.

AccuCount Blank Particles
ACBP-100-10	Cusabio	10 mL	EUR 230.4
Description: Flow Cytometry Particles For Absolute Cell Counting

AccuCount Blank Particles
ACBP-150-10	Spherotech	10 mL	EUR 237.6
Description: Flow Cytometry Particles For Absolute Cell Counting

AccuCount Blank Particles
ACBP-20-10	Spherotech	10 mL	EUR 230.4
Description: Flow Cytometry Particles For Absolute Cell Counting

AccuCount Blank Particles
ACBP-30-10	Spherotech	10 mL	EUR 225.6
Description: Flow Cytometry Particles For Absolute Cell Counting

Genie Blank Inserts
MIX5112	Scientific Laboratory Supplies	PK2	EUR 52.33

Blank-Control Protein Vector
PV001	ABM	500 ng	EUR 163.2

Blank-Control Protein Vector
PV002	ABM	500 ng	EUR 163.2

Resolution Std MeOH Blank
RSPEC-EPR003	Scientific Laboratory Supplies	100ML	EUR 216.6

Spectropho Blank 0.1M HCl
RSPEC00521	Scientific Laboratory Supplies	100ML	EUR 205.2

Spectropho Bandwidth Std Blank
RSPEC00531	Scientific Laboratory Supplies	100ML	EUR 205.2

1 mm Blank Comb, RS
2392066	Atto	4unit	EUR 336

2 mm Blank Comb, RS
2392067	Atto	3unit	EUR 333.6

1 mm Blank Comb, RM
2399041	Atto	4unit	EUR 326.4

Polyethylene QC Standard Blank - 5g
CRM-PEBLK	Scientific Laboratory Supplies	5G	EUR 53.58

Absorb Blank 0.005% Sulph Acid
RSPEC-CP0602	Scientific Laboratory Supplies	100ML	EUR 167.58

Spectropho Stray Light Blank Aqueous
RSPEC-EP00741	Scientific Laboratory Supplies	100ML	EUR 216.6

Spectropho Blank 0.001M Perch Acid
RSPEC00511	Scientific Laboratory Supplies	100ML	EUR 377.34

Spectropho Stray Light Blank Aqueous
RSPEC00541	Scientific Laboratory Supplies	100ML	EUR 205.2

100mm Blank 2011 ADR Labels Roll
DJR031	Scientific Laboratory Supplies	EACH	EUR 80.94

Kinesis 20mm Aluminimum Crimp Cap blank
CHR1158	Scientific Laboratory Supplies	PK500	EUR 45.61

Spectropho Bandwidth Std Blank (acc EP)
RSPEC-EP00731	Scientific Laboratory Supplies	100ML	EUR 216.6

Spectropho Blank 0.1M HCl in Cuv
RSPEC0052	Scientific Laboratory Supplies	EACH	EUR 379.62

Blank (Control) Dual Luciferase Stable Cell Line
m033	ABM	106 cells/ml, 1.0 ml	EUR 1704

Kerosene Blank for AA and ICP 500mL
KER-BLK	Scientific Laboratory Supplies	500ML	EUR 45.6

Poly(vinyl chloride) Phthalate Blank 1.5 g
CRM-PVCBLK	Scientific Laboratory Supplies	1.5G	EUR 47.88

Assurance Grade Water Blank for ICP 500mL
PLBLK-H2O	Scientific Laboratory Supplies	500ML	EUR 69.54

Assurance Grade Water Blank for ICP 500mL
PLBLK-HCL	Scientific Laboratory Supplies	500ML	EUR 61.56

Kinesis Ferrule Graphite / Vespel No Hole (Blank)
CHR1867	Scientific Laboratory Supplies	PK10	EUR 64.98

Spectropho Blank 0.001M Perch Acid in Cuv
RSPEC0051	Scientific Laboratory Supplies	EACH	EUR 379.62

MicroRNA Isolation Kit
KS341025	Biochain	1 kit	EUR 307.2
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Kerosene Blank for AA and ICP 1 Gallon
KER-BLK-G	Scientific Laboratory Supplies	1GALLON	EUR 143.64

Assurance Grade Water Blank for ICP 1 L
PLBLK-H2O-1L	Scientific Laboratory Supplies	1L	EUR 79.8

Assurance Grade Water Blank for ICP 2 L
PLBLK-H2O-2L	Scientific Laboratory Supplies	2L	EUR 102.6

Assurance Grade Water Blank for ICP 4 L
PLBLK-H2O-4L	Scientific Laboratory Supplies	4L	EUR 118.56

Assurance Grade Nitric Acid Blank for ICP 500mL
PLBLK-HNO3	Scientific Laboratory Supplies	500ML	EUR 69.54

Spectropho A/T Std Blank 0.005M Sulph Acid
RSPEC-EP00751	Scientific Laboratory Supplies	100ML	EUR 396.72

Nicotinic Acid Linear Set w/ Blank in Cuvs
RSPEC1027	Scientific Laboratory Supplies	PK5	EUR 2981.1

Cancer MicroRNA qPCR Array
RA610A-1	SBI	10 profiles	EUR 1406.4

Blank (Control) 3'UTR Luciferase Stable Cell Line
m018	ABM	1.0 ml	EUR 1581.6

Blank (Control) 3'UTR GFP Stable Cell Line
m019	ABM	1.0 ml	EUR 1581.6

Claritas PPT Grade Water Blank for ICP-MS 125mL
CLBLK-H2O	Scientific Laboratory Supplies	125ML	EUR 70.68

Kinesis Ferrule Graphite / Vespel No Hole (Short and Blank)
CHR1883	Scientific Laboratory Supplies	PK10	EUR 64.98

Blank Burette Holder for HI-931 and HI-932
TIT1024	Scientific Laboratory Supplies	EACH	EUR 68.4

Stray Light Inorg Cut-Off Filter KCl w/ Blank
RSPEC-EP00621	Scientific Laboratory Supplies	100ML	EUR 396.72

Resolution Std Toluene in MeOH w/ Blank in Cuvettes
RSPEC-EPR001	Scientific Laboratory Supplies	PK2	EUR 1177.62

Spectropho Bandwidth Std Toluene in Hexane and Blank Cuvs
RSPEC1031	Scientific Laboratory Supplies	PK2	EUR 2420.22

Sulfur Blank in no.2 Diesel Fuel 100 grams
SDFS-BLK-Y	Scientific Laboratory Supplies	100ML	EUR 102.6

Dynamin inhibitory peptide
A1046-1	ApexBio	1 mg	EUR 226.8
Description: Dynamin Inhibitory Peptide is a peptide (Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro) inhibitor of the GTPase dynamin.Dynamin is a 100-kDa large GTPase that functions to tabulate membranes and liberate nascent vesicles from the Golgi apparatus and plasma membrane.

Dynamin inhibitory peptide
A1046-10	ApexBio	10 mg	EUR 895.2
Description: Dynamin Inhibitory Peptide is a peptide (Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro) inhibitor of the GTPase dynamin.Dynamin is a 100-kDa large GTPase that functions to tabulate membranes and liberate nascent vesicles from the Golgi apparatus and plasma membrane.

Dynamin inhibitory peptide
A1046-25	ApexBio	25 mg	EUR 1228.8
Description: Dynamin Inhibitory Peptide is a peptide (Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro) inhibitor of the GTPase dynamin.Dynamin is a 100-kDa large GTPase that functions to tabulate membranes and liberate nascent vesicles from the Golgi apparatus and plasma membrane.

Dynamin inhibitory peptide
A1046-5	ApexBio	5 mg	EUR 560.4
Description: Dynamin Inhibitory Peptide is a peptide (Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro) inhibitor of the GTPase dynamin.Dynamin is a 100-kDa large GTPase that functions to tabulate membranes and liberate nascent vesicles from the Golgi apparatus and plasma membrane.

bFGF Inhibitory Peptide
5-00757	CHI Scientific	4 x 5mg	Ask for price

Macrophage Inhibitory Peptide
5-01493	CHI Scientific	4 x 5mg	Ask for price

Macrophage Inhibitory Peptide
20-abx265724	Abbexa	EUR 393.60 EUR 594.00 EUR 326.40	10 mg 25 mg 5 mg

bFGF Inhibitory Peptide
20-abx265957	Abbexa	EUR 460.80 EUR 710.40 EUR 360.00	10 mg 25 mg 5 mg

INHIBITORY MOLD AGAR
I09-102-10kg	Alphabiosciences	10 kg	EUR 3477.6

INHIBITORY MOLD AGAR
I09-102-2kg	Alphabiosciences	2kg	EUR 802.8

INHIBITORY MOLD AGAR
I09-102-500g	Alphabiosciences	500 g	EUR 261.6

C5a Inhibitory Sequence
H-8135.0005	Bachem	5.0mg	EUR 849.6
Description: Sum Formula: C51H86N12O9; CAS# [133214-60-5]

C5a Inhibitory Sequence
H-8135.0025	Bachem	25.0mg	EUR 3286.8
Description: Sum Formula: C51H86N12O9; CAS# [133214-60-5]

Macrophage Inhibitory Peptide
H-4300.0050	Bachem	50.0mg	EUR 297.6
Description: Sum Formula: C15H28N4O5; CAS# [41961-56-2]

Macrophage Inhibitory Peptide
H-4300.0250	Bachem	250.0mg	EUR 1082.4
Description: Sum Formula: C15H28N4O5; CAS# [41961-56-2]

MicroRNA scramble in CD511 - Virus
PMIRH000VA-1	SBI	1x10^6 IFUs	EUR 937.2

MicroRNA Precursor Pooled Plasmid Library
PMIRHPLPA-1	SBI	1 aliquot plasmid DNA	EUR 60

SanPrep Column microRNA Miniprep Kit
SK8811	Bio Basic	50prep	EUR 151.32

Stem Cell MicroRNA Profiling Panel
RA620A-1	SBI	10 profiles	EUR 1406.4

Claritas PPT Grade Hydrochloric Acid Blank for ICP-MS 125mL
CLBLK-HCL	Scientific Laboratory Supplies	125ML	EUR 70.68

Claritas PPT Grade Nitric Acid Blank for ICP-MS 125mL
CLBLK-HNO3	Scientific Laboratory Supplies	125ML	EUR 72.96

Spectropho Pot Dichro Linear Std Set w/ Blank in Cuvs
RSPEC1022	Scientific Laboratory Supplies	PK6	EUR 3499.8

bFGF Inhibitory Peptide II
5-00758	CHI Scientific	4 x 1mg	Ask for price

Fibrinogen Binding Inhibitory Peptide
5-01135	CHI Scientific	4 x 5mg	Ask for price

Gastric Inhibitory Peptide (GIP)
20-abx265278	Abbexa	EUR 376.80 EUR 510.00 EUR 744.00	0.5 mg 1 mg 2.5 mg

Fibrinogen Binding Inhibitory Peptide
20-abx266336	Abbexa	EUR 594.00 EUR 1078.80 EUR 427.20	10 mg 25 mg 5 mg

Melanoma Inhibitory Activity Antibody
DF14235	Affbiotech	100ul	EUR 420

LIF/Leukemia inhibitory factor
E21-017	EnoGene	10ug	EUR 411.6

LIF/Leukemia inhibitory factor
E21-690	EnoGene	10ug	EUR 411.6

Minimal Inhibitory Concentration Kit
K195-2500	Biovision		EUR 836.4

Minimal Inhibitory Concentration Kit
K195-500	Biovision		EUR 574.8

Gastric Inhibitory Polypeptide (human)
H-5645.0500	Bachem	0.5mg	EUR 471.6
Description: Sum Formula: C226H338N60O66S; CAS# [100040-31-1]

Gastric Inhibitory Polypeptide (human)
H-5645.1000	Bachem	1.0mg	EUR 835.2
Description: Sum Formula: C226H338N60O66S; CAS# [100040-31-1]

Gastric Inhibitory Polypeptide (porcine)
H-6220.0500	Bachem	0.5mg	EUR 471.6
Description: Sum Formula: C225H342N60O66S; CAS# [11063-17-5] net

Gastric Inhibitory Polypeptide (porcine)
H-6220.1000	Bachem	1.0mg	EUR 835.2
Description: Sum Formula: C225H342N60O66S; CAS# [11063-17-5] net

ATPase Inhibitory Factor 1
PR27231	Neuromics	5 ug	EUR 229.2

Stray Light Inorg Cut-Off Filter KCl w/ Blank in Cuvs
RSPEC-EP0062	Scientific Laboratory Supplies	PK2	EUR 1020.3

Spectropho Bandwidth Std Toluene in Hexane and Blank (acc EP) Cuvs
RSPEC-EP0063	Scientific Laboratory Supplies	PK2	EUR 2539.92

OncoMir pooled microRNA precursor virus library
PMIRHOPLVA-1	SBI	1 virus aliquot	EUR 1429.2

MicroRNA precursor pooled library, HT prepackaged
PMIRHPLVAHT-1	SBI	10 virus aliquots	EUR 12042

Human microRNA-210(miR-210)ELISA
QY-E05678	Qayee Biotechnology	96T	EUR 433.2

hsa-miRNome MicroRNA Profiling Kit [Human]
RA660A-1	SBI	20 profiles	EUR 2212.8

mmu-miRNome MicroRNA Profiling Kit [Mouse]
RA670A-1	SBI	20 profiles	EUR 2046

rno-miRNome MicroRNA Profiling Kit [Rat]
RA680B-1	SBI	20 complete profiles	EUR 2006.4

Sulfur Blank for AA and ICP 100 grams in Base Oil 20
DSS8-Y	Scientific Laboratory Supplies	100ML	EUR 100.32

Kinesis CV Outlet Washer (Blank) Gilson 5/10/25 SC and WSC
CHR6237	Scientific Laboratory Supplies	EACH	EUR 20.52

Trace metals on quartz filter paper includes 5 spiked filtersand 1 blank
QFM-SPIKE-1	Scientific Laboratory Supplies	EACH	EUR 171

Limit of Stray Light Blank 340nm for use w/ Na Nitrite Std
RSPEC-CP0362	Scientific Laboratory Supplies	100ML	EUR 201.78

Limit of Stray Light Blank 220nm for use w/ Na Iodide Std
RSPEC-CP0372	Scientific Laboratory Supplies	100ML	EUR 167.58

Stray Light Inorg Cut-Off Filter KCl w/ Blank x2 in Cuvs
RSPEC-EP0062X2BU	Scientific Laboratory Supplies	PK3	EUR 1088.7

Spectropho Bandwidth Std Toluene in Hexane and 2x Blank (acc EP) Cuvs
RSPEC-EP0063X2BU	Scientific Laboratory Supplies	PK3	EUR 2297.1

miRNA Kit
20-abx098094	Abbexa	EUR 126.00 EUR 627.60	2 rxns 50 rxns

miRNA Inhibitor
M1265-10	Biovision		EUR 666

miRNA Inhibitor
M1265-2	Biovision		EUR 424.8

miRNA Inhibitor
M1265-3	Biovision		EUR 451.2

miRNA Inhibitor
M1265-4	Biovision		EUR 489.6

miRNA Inhibitor
M1265-5	Biovision		EUR 516

miRNA Inhibitor
M1265-6	Biovision		EUR 542.4

miRNA Inhibitor
M1265-7	Biovision		EUR 568.8

miRNA Inhibitor
M1265-8	Biovision		EUR 594

miRNA Inhibitor
M1265-9	Biovision		EUR 633.6

Recombinant Human Leukemia Inhibitory Factor
7-01228	CHI Scientific	2µg	Ask for price

Recombinant Human Leukemia Inhibitory Factor
7-01229	CHI Scientific	10µg	Ask for price

Recombinant Human Leukemia Inhibitory Factor
7-01230	CHI Scientific	1mg	Ask for price

Recombinant Mouse Leukemia Inhibitory Factor
7-01231	CHI Scientific	2µg	Ask for price

Recombinant Mouse Leukemia Inhibitory Factor
7-01232	CHI Scientific	10µg	Ask for price

Recombinant Mouse Leukemia Inhibitory Factor
7-01233	CHI Scientific	1mg	Ask for price

Cdk2/Cyclin Inhibitory Peptide I
A1107-1	ApexBio	1 mg	EUR 115.2
Description: Cyclin-dependent kinase 2 also known as cell division protein kinase 2(1). The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases.

Cdk2/Cyclin Inhibitory Peptide I
A1107-10	ApexBio	10 mg	EUR 338.4
Description: Cyclin-dependent kinase 2 also known as cell division protein kinase 2(1). The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases.

Cdk2/Cyclin Inhibitory Peptide I
A1107-25	ApexBio	25 mg	EUR 448.8
Description: Cyclin-dependent kinase 2 also known as cell division protein kinase 2(1). The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases.

Cdk2/Cyclin Inhibitory Peptide I
A1107-5	ApexBio	5 mg	EUR 226.8
Description: Cyclin-dependent kinase 2 also known as cell division protein kinase 2(1). The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases.

Gastric Inhibitory Peptide (GIP), human
5-01186	CHI Scientific	0.4 x 5mg	Ask for price

Leukemia inhibitory factor Protein (OVA)
20-abx165566	Abbexa	EUR 693.60 EUR 309.60 EUR 2064.00 EUR 828.00 EUR 510.00	100 ug 10 ug 1 mg 200 ug 50 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx102564	Abbexa	EUR 376.80 EUR 159.60 EUR 994.80 EUR 526.80 EUR 326.40	100 ug 10 ug 1 mg 200 ug 50 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx102565	Abbexa	EUR 493.20 EUR 159.60 EUR 1362.00 EUR 661.20 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx104912	Abbexa	EUR 526.80 EUR 159.60 EUR 1479.60 EUR 710.40 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx005951	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Leukemia Inhibitory Factor (LIF) Antibody
20-abx007853	Abbexa	EUR 360.00 EUR 526.80 EUR 226.80	100 ul 200 ul 30 ul

Leukemia Inhibitory Factor (LIF) Antibody
20-abx121636	Abbexa	EUR 360.00 EUR 526.80 EUR 226.80	100 ul 200 ul 30 ul

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx130323	Abbexa	EUR 510.00 EUR 159.60 EUR 1412.40 EUR 693.60 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx131206	Abbexa	EUR 477.60 EUR 159.60 EUR 1312.80 EUR 644.40 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx131964	Abbexa	EUR 376.80 EUR 944.40 EUR 493.20 EUR 184.80 EUR 309.60	100 ug 1 mg 200 ug 20 ug 50 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx131965	Abbexa	EUR 376.80 EUR 944.40 EUR 493.20 EUR 184.80 EUR 309.60	100 ug 1 mg 200 ug 20 ug 50 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx131966	Abbexa	EUR 376.80 EUR 927.60 EUR 493.20 EUR 184.80 EUR 309.60	100 ug 1 mg 200 ug 20 ug 50 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx128739	Abbexa	EUR 477.60 EUR 159.60 EUR 1328.40 EUR 644.40 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Leukemia Inhibitory Factor (LIF) Antibody
abx033095-400ul	Abbexa	400 ul	EUR 627.6

Leukemia Inhibitory Factor (LIF) Antibody
abx033095-80l	Abbexa	80 µl	EUR 343.2

Virus Inhibitory Protein (Viperin) Antibody
20-abx178882	Abbexa	EUR 1579.20 EUR 744.00	1 mg 200 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx321740	Abbexa	EUR 360.00 EUR 292.80	100 ul 50 ul

ATPase Inhibitory Factor 1 Protein
20-abx260918	Abbexa	EUR 4101.60 EUR 393.60 EUR 276.00	1 mg 20 ug 5 ug

Leukemia Inhibitory Factor, Yeast Protein
20-abx261874	Abbexa	EUR 5388.00 EUR 393.60 EUR 276.00	1 mg 25 ug 5 ug

Gastric Inhibitory Polypeptide (GIP) Peptide
20-abx262609	Abbexa	EUR 393.60 EUR 7676.40 EUR 276.00	10 ug 1 mg 2 µg

Leukemia Inhibitory Factor (LIF) Antibody
20-abx323565	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

Melanoma Inhibitory Activity (MIA) Antibody
abx430034-200ul	Abbexa	200 ul	EUR 460.8

Leukemia Inhibitory Factor (LIF) Antibody
abx431389-200ul	Abbexa	200 ul	EUR 460.8

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx339422	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx339737	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Melanoma Inhibitory Activity (MIA) Antibody
abx235173-100ug	Abbexa	100 ug	EUR 577.2

Leukemia Inhibitory Factor (LIF) Antibody
20-abx213624	Abbexa	EUR 493.20 EUR 360.00	100 ul 50 ul

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx172523	Abbexa	EUR 1011.60 EUR 526.80	1 mg 200 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx173341	Abbexa	EUR 360.00 EUR 844.80 EUR 427.20 EUR 184.80 EUR 292.80	100 ug 1 mg 200 ug 20 ug 50 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx173342	Abbexa	EUR 1011.60 EUR 526.80	1 mg 200 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx173343	Abbexa	EUR 1095.60 EUR 560.40	1 mg 200 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx176562	Abbexa	EUR 493.20 EUR 159.60 EUR 1362.00 EUR 661.20 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx176563	Abbexa	EUR 1362.00 EUR 661.20	1 mg 200 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx176564	Abbexa	EUR 1362.00 EUR 661.20	1 mg 200 ug

Gastric Inhibitory Polypeptide (GIP) Antibody
20-abx176565	Abbexa	EUR 510.00 EUR 159.60 EUR 1412.40 EUR 693.60 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx177341	Abbexa	EUR 1412.40 EUR 693.60	1 mg 200 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx177342	Abbexa	EUR 1545.60 EUR 744.00	1 mg 200 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx177343	Abbexa	EUR 1545.60 EUR 744.00	1 mg 200 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx177344	Abbexa	EUR 1579.20 EUR 760.80	1 mg 200 ug

Leukemia Inhibitory Factor (LIF) Antibody
20-abx177345	Abbexa	EUR 577.20 EUR 159.60 EUR 1680.00 EUR 794.40 EUR 427.20	100 ug 10 ug 1 mg 200 ug 50 ug

Virus Inhibitory Protein (Viperin) Antibody
20-abx175097	Abbexa	EUR 1111.20 EUR 560.40	1 mg 200 ug

Active Leukemia Inhibitory Factor (LIF)
4-APA085Hu01	Cloud-Clone	EUR 945.76 EUR 376.80 EUR 3216.58 EUR 1152.19 EUR 2184.38 EUR 708.00 EUR 7861.44	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Leukemia Inhibitory Factor expressed in: E.coli

Autocamtide-2-related inhibitory peptide
B6831-1	ApexBio	1 mg	EUR 184.8
Description: IC50: 40 nM for CaM-kinase II [1].

Autocamtide-2-related inhibitory peptide
B6831-10	ApexBio	10 mg	EUR 999.6
Description: IC50: 40 nM for CaM-kinase II [1].

Autocamtide-2-related inhibitory peptide
B6831-5	ApexBio	5 mg	EUR 622.8
Description: IC50: 40 nM for CaM-kinase II [1].

Beta-lactamase inhibitory protein Antibody
1-CSB-PA327444LA01FOA	Cusabio	EUR 380.40 EUR 402.00	100ug 50ug
Description: A polyclonal antibody against Beta-lactamase inhibitory protein. Recognizes Beta-lactamase inhibitory protein from Streptomyces clavuligerus. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:5000

Rat Neurite outgrowth inhibitory peptide
Nogo-P4	Alpha Diagnostics	1 mg	EUR 315.6

MIF/Macrophage migration inhibitory factor
E21-H33	EnoGene	10ug	EUR 411.6

Gastric Inhibitory Peptide (GIP), human
HY-P0276	MedChemExpress	5mg	EUR 2043.6

(Pro3)-Gastric Inhibitory Polypeptide (human)
H-7584.0500	Bachem	0.5mg	EUR 177.6
Description: Sum Formula: C226H338N60O64S; CAS# [299898-52-5] net

(Pro3)-Gastric Inhibitory Polypeptide (human)
H-7584.1000	Bachem	1.0mg	EUR 277.2
Description: Sum Formula: C226H338N60O64S; CAS# [299898-52-5] net

Autocamtide-2-Related Inhibitory Peptide
H-3384.0001	Bachem	1.0mg	EUR 414
Description: Sum Formula: C64H116N22O19; CAS# [167114-91-2] net

Autocamtide-2-Related Inhibitory Peptide
H-3384.0005	Bachem	5.0mg	EUR 1545.6
Description: Sum Formula: C64H116N22O19; CAS# [167114-91-2] net

Recombinant human Gastric inhibitory polypeptide
P1555	FN Test	100ug	Ask for price
Description: Recombinant protein for human Gastric inhibitory polypeptide

Leukemia Inhibitory Factor (LIF), human
PR16101	Neuromics	5 ug	EUR 522

Leukemia Inhibitory Factor (LIF), mouse
PR16102	Neuromics	5 ug	EUR 522

Leukemia Inhibitory Factor (LIF), rat
PR16103	Neuromics	5 ug	EUR 522

Recombinant Leukemia Inhibitory Factor (LIF)
4-RPA085Ca01	Cloud-Clone	EUR 646.85 EUR 296.40 EUR 2095.68 EUR 778.56 EUR 1437.12 EUR 508.80 EUR 5059.20	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Dog Leukemia Inhibitory Factor expressed in: E.coli

Recombinant Leukemia Inhibitory Factor (LIF)
4-RPA085Hu01	Cloud-Clone	EUR 532.87 EUR 266.40 EUR 1668.29 EUR 636.10 EUR 1152.19 EUR 432.00 EUR 3990.72	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Leukemia Inhibitory Factor expressed in: E.coli

Recombinant Leukemia Inhibitory Factor (LIF)
4-RPA085Mu01	Cloud-Clone	EUR 565.13 EUR 274.80 EUR 1789.25 EUR 676.42 EUR 1232.83 EUR 453.60 EUR 4293.12	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Leukemia Inhibitory Factor expressed in: E.coli

Recombinant Leukemia Inhibitory Factor (LIF)
4-RPA085Ra01	Cloud-Clone	EUR 496.32 EUR 256.80 EUR 1531.20 EUR 590.40 EUR 1060.80 EUR 408.00 EUR 3648.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Recombinant Leukemia Inhibitory Factor (LIF) expressed in: E.coli

LIF, Leukemia inhibitory factor, human
RC214-18	Bio Basic	2ug	EUR 121.6

Recombinant Gastric Inhibitory Polypeptide (GIP)
4-RPA882Hu01	Cloud-Clone	EUR 496.32 EUR 256.80 EUR 1531.20 EUR 590.40 EUR 1060.80 EUR 408.00 EUR 3648.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Gastric Inhibitory Polypeptide expressed in: E.coli

Recombinant Gastric Inhibitory Polypeptide (GIP)
4-RPA882Ra01	Cloud-Clone	EUR 528.58 EUR 265.20 EUR 1652.16 EUR 630.72 EUR 1141.44 EUR 429.60 EUR 3950.40	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Gastric Inhibitory Polypeptide expressed in: E.coli

anti-ATPase Inhibitory Factor 1
YF-PA21797	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to ATPase Inhibitory Factor 1

Anti-Melanoma Inhibitory Activity (3A6)
YF-MA16304	Abfrontier	100 ug	EUR 435.6
Description: Mouse monoclonal to Melanoma Inhibitory Activity

Gip Antibody / Gastric inhibitory polypeptide
R32431	NSJ Bioreagents	100 ug	EUR 419

GIP Antibody / Gastric inhibitory polypeptide
R32434	NSJ Bioreagents	100 ug	EUR 419

miRZip-1 anti-miR-1 microRNA construct
MZIP1-PA-1	SBI	Bacterial Streak	EUR 820.8

miRZip-100 anti-miR-100 microRNA construct
MZIP100-PA-1	SBI	Bacterial Streak	EUR 820.8

miRZip-101 anti-miR-101 microRNA construct
MZIP101-PA-1	SBI	Bacterial Streak	EUR 820.8

miRZip-103 anti-miR-103 microRNA construct
MZIP103-PA-1	SBI	Bacterial Streak	EUR 820.8

miRZip-106a anti-miR-106a microRNA construct
MZIP106a-PA-1	SBI	Bacterial Streak	EUR 820.8

miRZip-106b anti-miR-106b microRNA construct
MZIP106b-PA-1	SBI	Bacterial Streak	EUR 820.8

Right here, we deal with plant derived chemical substances, and supply an up to date literature overview on the anti-biofilm properties of terpenes, flavonoids, alkaloids, and phenolic compounds. Furthermore, each time info is accessible, we additionally report the mechanisms of motion.