Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

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This research aimed to organize the sugar business for the attainable introduction of genetically modified (GM) sugarcane and derived retail sugar merchandise and to deal with a number of potential public considerations concerning the traits and security of those merchandise. GM sugarcane strains with built-in Cry1Ab and EPSPS overseas genes have been used for GM sugar manufacturing.

Conventional PCR, real-time fluorescent quantitative PCR (RT-qPCR), and enzyme-linked immunosorbent assay (ELISA) have been carried out in analyzing leaves, stems, and different derived supplies throughout sugar manufacturing, corresponding to fibers, clarified juices, filter mud, syrups, molasses, and ultimate GM sugar product. The toxicity of GM sugar was examined with a feeding bioassay utilizing Helicoverpa armigera larvae. PCR and RT-qPCR outcomes confirmed that the leaves, stems, fibers, juices, syrups, filter mud, molasses, and white granulated sugar from GM sugarcane might be distinguished from these derived from non-GM sugarcane. The RT-qPCR detection technique utilizing brief amplified product primers was extra correct than the normal PCR technique.

Molecular evaluation outcomes indicated that hint quantities of DNA residues stay in GM sugar, and thus it may be precisely characterised utilizing molecular evaluation strategies. ELISA outcomes confirmed that solely the leaves, stems, fibers, and juices sampled from the GM sugarcane differed from these derived from the non-GM sugarcane, indicating that filter mud, syrup, molasses, and white sugar didn’t include detectable Cry1Ab and EPSPS proteins.

Toxicity evaluation confirmed that the GM sugar was not poisonous to the H. armigera larvae. The ultimate outcomes confirmed that the GM sugar had no lively proteins regardless of containing hint quantities of DNA residues. This discovering will assist to pave the best way for the commercialization of GM sugarcane and manufacturing of GM sugar.

Lysine-Arginine Superior Glycation Finish-Product Cross-links and the Impact on Collagen Construction: A Molecular Dynamics Examine

The buildup of superior glycation end-products is a elementary course of that’s central to age-related decline in musculoskeletal tissues and locomotor system operate and different collagen-rich tissues. Nevertheless, though computational research of superior glycation end-product cross-links may very well be immensely worthwhile, this space stays largely unexplored given the restricted availability of structural parameters for the derivation of power fields for Molecular Dynamics simulations.

On this article, we current the bonded power constants, atomic partial prices and geometry of the arginine-lysine cross-links DOGDIC, GODIC and MODIC. We now have carried out in vacuo Molecular Dynamics simulations to validate their implementation in opposition to quantum mechanical frequency calculations. A DOGDIC superior glycation end-product cross-link was then inserted right into a mannequin collagen fibril to discover structural modifications of collagen and dynamics in interstitial water. In contrast to our earlier research of glucosepane, our findings recommend that intra-collagen DOGDIC cross-links furthers intra-collagen peptide hydrogen-bonding and doesn’t promote the diffusion of water by way of the collagen triple helices. This text is protected by copyright. All rights reserved.

Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

Genomics-directed activation of cryptic pure product pathways deciphers codes for biosynthesis and molecular operate

Pure merchandise, which might be remoted from residing organisms worldwide, have performed a pivotal position in drug discovery since historical instances. Nevertheless, it has grow to be tougher to determine a structurally novel molecule with promising organic exercise for pharmaceutical growth, primarily because of the restricted methodologies for his or her acquisition. On this assessment, we summarize our latest research that activate the biosynthetic potential of filamentous fungi by genetic engineering to harness the metabolic move for the environment friendly manufacturing of unprecedented pure merchandise.

The latest revolution in genome sequencing know-how allows the buildup of huge quantities of knowledge on biosynthetic genes, the blueprint of the molecular building. Using the established heterologous expression system, activation of the pathway-specific transcription issue coupled with a knockout technique, and manipulating the worldwide regulatory gene, the biosynthetic genes have been exploited to activate biosynthetic pathways and decipher the encoded enzyme features. We present that this system was useful for buying fungal treasures for drug discovery. These research additionally enabled the investigation of the molecular operate of pure merchandise in fungal growth.

Digital screening and molecular simulation research of pure merchandise database for lead identification of novel coronavirus fundamental protease inhibitors

3CL like protease (3CLpro or Mpro) is likely one of the fundamental proteases of 2019-nCoV. The 3CLpro is a nonstructural protein of SARS-CoV and has an important position in viral replication and transcription, thus, may very well be a possible goal for anti-SARS drug growth. The current research employed ligand- and structure-based approaches to determine the potent inhibitors of 2019-nCoV protease.

The e-pharmacophore developed from 3CLpro-1 yielded digital hits, that have been subjected by way of drug likeliness and PAINS filters to take away interfering compounds. Additional complete docking research, free power calculations and ADMET research resulted in two digital leads- MolPort-000-410-348 and MolPort-002-530-156. The compounds MolPort-000-410-348 and MolPort-002-530-156 displayed good docking rating of -12.09 and -13.38 Kcal/mol and free binding power of -63.34 ± 2.03 and -61.52 ± 2.24 Kcal/mol, respectively.

Human pre-microRNA Expression Construct let-7a-1
PMIRHlet7a1PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7a-2
PMIRHlet7a2PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7a-3
PMIRHlet7a3PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7f-1
PMIRHlet7f1PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7f-2
PMIRHlet7f2PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-95
PMIRH95PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-96
PMIRH96PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-98
PMIRH98PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-21
PMIRH21PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-22
PMIRH22PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-28
PMIRH28PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-31
PMIRH31PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-32
PMIRH32PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-490
PMIRH490PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-491
PMIRH491PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-492
PMIRH492PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-493
PMIRH493PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-494
PMIRH494PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-495
PMIRH495AA-1 Miniprep DNA
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-495
PMIRH495PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-496
PMIRH496PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-498
PMIRH498PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-499
PMIRH499PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-501
PMIRH501PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-503
PMIRH503PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-504
PMIRH504PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-505
PMIRH505PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-506
PMIRH506PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-507
PMIRH507PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-508
PMIRH508PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-510
PMIRH510PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-522
PMIRH522PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-523
PMIRH523PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-524
PMIRH524PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-525
PMIRH525PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-527
PMIRH527PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-532
PMIRH532PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-539
PMIRH539PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-541
PMIRH541PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-542
PMIRH542PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-543
PMIRH543PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-544
PMIRH544PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-545
PMIRH545PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-549
PMIRH549PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-552
PMIRH552PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-553
PMIRH553PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-554
PMIRH554PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-555
PMIRH555PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-556
PMIRH556PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-557
PMIRH557PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-558
PMIRH558PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-561
PMIRH561PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-562
PMIRH562PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-563
PMIRH563PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-564
PMIRH564PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-566
PMIRH566PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-569
PMIRH569PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-570
PMIRH570PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-571
PMIRH571PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-572
PMIRH572PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-574
PMIRH574PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-575
PMIRH575PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-577
PMIRH577PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-578
PMIRH578PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-579
PMIRH579PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-580
PMIRH580PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-581
PMIRH581PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-582
PMIRH582PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-583
PMIRH583PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-584
PMIRH584PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-585
PMIRH585PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-586
PMIRH586PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-587
PMIRH587PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-588
PMIRH588PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-589
PMIRH589PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-590
PMIRH590PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-591
PMIRH591PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-592
PMIRH592PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-593
PMIRH593PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-595
PMIRH595PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-596
PMIRH596PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-597
PMIRH597PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-598
PMIRH598PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-599
PMIRH599PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-600
PMIRH600PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-601
PMIRH601PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-602
PMIRH602PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-603
PMIRH603PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-604
PMIRH604PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-605
PMIRH605PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-606
PMIRH606PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-607
PMIRH607PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-608
PMIRH608PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-609
PMIRH609PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-610
PMIRH610PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-611
PMIRH611PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-612
PMIRH612PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-613
PMIRH613PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-614
PMIRH614PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-616
PMIRH616PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-617
PMIRH617PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-618
PMIRH618PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-621
PMIRH621PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-622
PMIRH622PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-623
PMIRH623PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-624
PMIRH624PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-625
PMIRH625PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-626
PMIRH626PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-627
PMIRH627PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-628
PMIRH628PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-629
PMIRH629PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-630
PMIRH630PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-631
PMIRH631PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-632
PMIRH632PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-633
PMIRH633PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-634
PMIRH634PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-637
PMIRH637PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-638
PMIRH638PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-639
PMIRH639PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-640
PMIRH640PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-641
PMIRH641PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-642
PMIRH642PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-643
PMIRH643PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-644
PMIRH644PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-645
PMIRH645PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-646
PMIRH646PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-647
PMIRH647PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-648
PMIRH648PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-650
PMIRH650PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-651
PMIRH651PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-652
PMIRH652AA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-652
PMIRH652PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-653
PMIRH653PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-654
PMIRH654PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-655
PMIRH655PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-656
PMIRH656PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-657
PMIRH657PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-658
PMIRH658PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-659
PMIRH659PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-660
PMIRH660PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-661
PMIRH661PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-663
PMIRH663PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-664
PMIRH664PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-665
PMIRH665AA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-665
PMIRH665PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-668
PMIRH668PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-671
PMIRH671PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-675
PMIRH675PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-708
PMIRH708PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-720
PMIRH720AA-1 Miniprep DNA
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-720
PMIRH720PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-744
PMIRH744PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-758
PMIRH758PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-760
PMIRH760PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-765
PMIRH765PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-767
PMIRH767PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-768
PMIRH768PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-769
PMIRH769PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-770
PMIRH770PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-802
PMIRH802PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-873
PMIRH873PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-874
PMIRH874PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-875
PMIRH875PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-876
PMIRH876PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-877
PMIRH877PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-885
PMIRH885PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-886
PMIRH886PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-887
PMIRH887PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-888
PMIRH888PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-889
PMIRH889PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-890
PMIRH890PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-921
PMIRH921PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-922
PMIRH922PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-924
PMIRH924PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-933
PMIRH933PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-934
PMIRH934PA-1 Bacterial Streak
EUR 620

The compounds additionally exhibited passable predicted ADMET profile and have been subjected to molecular dynamic (MD) research. The MD simulation produced secure complexes of those ligands with 3CLpro protein and ligand RMSD in acceptable limits. Communicated by Ramaswamy H. Sarma.

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