Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

This research aimed to organize the sugar business for the attainable introduction of genetically modified (GM) sugarcane and derived retail sugar merchandise and to deal with a number of potential public considerations concerning the traits and security of those merchandise. GM sugarcane strains with built-in Cry1Ab and EPSPS overseas genes have been used for GM sugar manufacturing.

Conventional PCR, real-time fluorescent quantitative PCR (RT-qPCR), and enzyme-linked immunosorbent assay (ELISA) have been carried out in analyzing leaves, stems, and different derived supplies throughout sugar manufacturing, corresponding to fibers, clarified juices, filter mud, syrups, molasses, and ultimate GM sugar product. The toxicity of GM sugar was examined with a feeding bioassay utilizing Helicoverpa armigera larvae. PCR and RT-qPCR outcomes confirmed that the leaves, stems, fibers, juices, syrups, filter mud, molasses, and white granulated sugar from GM sugarcane might be distinguished from these derived from non-GM sugarcane. The RT-qPCR detection technique utilizing brief amplified product primers was extra correct than the normal PCR technique.

Molecular evaluation outcomes indicated that hint quantities of DNA residues stay in GM sugar, and thus it may be precisely characterised utilizing molecular evaluation strategies. ELISA outcomes confirmed that solely the leaves, stems, fibers, and juices sampled from the GM sugarcane differed from these derived from the non-GM sugarcane, indicating that filter mud, syrup, molasses, and white sugar didn’t include detectable Cry1Ab and EPSPS proteins.

Toxicity evaluation confirmed that the GM sugar was not poisonous to the H. armigera larvae. The ultimate outcomes confirmed that the GM sugar had no lively proteins regardless of containing hint quantities of DNA residues. This discovering will assist to pave the best way for the commercialization of GM sugarcane and manufacturing of GM sugar.

Lysine-Arginine Superior Glycation Finish-Product Cross-links and the Impact on Collagen Construction: A Molecular Dynamics Examine

The buildup of superior glycation end-products is a elementary course of that’s central to age-related decline in musculoskeletal tissues and locomotor system operate and different collagen-rich tissues. Nevertheless, though computational research of superior glycation end-product cross-links may very well be immensely worthwhile, this space stays largely unexplored given the restricted availability of structural parameters for the derivation of power fields for Molecular Dynamics simulations.

On this article, we current the bonded power constants, atomic partial prices and geometry of the arginine-lysine cross-links DOGDIC, GODIC and MODIC. We now have carried out in vacuo Molecular Dynamics simulations to validate their implementation in opposition to quantum mechanical frequency calculations. A DOGDIC superior glycation end-product cross-link was then inserted right into a mannequin collagen fibril to discover structural modifications of collagen and dynamics in interstitial water. In contrast to our earlier research of glucosepane, our findings recommend that intra-collagen DOGDIC cross-links furthers intra-collagen peptide hydrogen-bonding and doesn’t promote the diffusion of water by way of the collagen triple helices. This text is protected by copyright. All rights reserved.

 Molecular and Toxicity Analyses of White Granulated Sugar and Other Processing Products Derived From Transgenic Sugarcane

Genomics-directed activation of cryptic pure product pathways deciphers codes for biosynthesis and molecular operate

Pure merchandise, which might be remoted from residing organisms worldwide, have performed a pivotal position in drug discovery since historical instances. Nevertheless, it has grow to be tougher to determine a structurally novel molecule with promising organic exercise for pharmaceutical growth, primarily because of the restricted methodologies for his or her acquisition. On this assessment, we summarize our latest research that activate the biosynthetic potential of filamentous fungi by genetic engineering to harness the metabolic move for the environment friendly manufacturing of unprecedented pure merchandise.

The latest revolution in genome sequencing know-how allows the buildup of huge quantities of knowledge on biosynthetic genes, the blueprint of the molecular building. Using the established heterologous expression system, activation of the pathway-specific transcription issue coupled with a knockout technique, and manipulating the worldwide regulatory gene, the biosynthetic genes have been exploited to activate biosynthetic pathways and decipher the encoded enzyme features. We present that this system was useful for buying fungal treasures for drug discovery. These research additionally enabled the investigation of the molecular operate of pure merchandise in fungal growth.

Digital screening and molecular simulation research of pure merchandise database for lead identification of novel coronavirus fundamental protease inhibitors

3CL like protease (3CLpro or Mpro) is likely one of the fundamental proteases of 2019-nCoV. The 3CLpro is a nonstructural protein of SARS-CoV and has an important position in viral replication and transcription, thus, may very well be a possible goal for anti-SARS drug growth. The current research employed ligand- and structure-based approaches to determine the potent inhibitors of 2019-nCoV protease.

The e-pharmacophore developed from 3CLpro-1 yielded digital hits, that have been subjected by way of drug likeliness and PAINS filters to take away interfering compounds. Additional complete docking research, free power calculations and ADMET research resulted in two digital leads- MolPort-000-410-348 and MolPort-002-530-156. The compounds MolPort-000-410-348 and MolPort-002-530-156 displayed good docking rating of -12.09 and -13.38 Kcal/mol and free binding power of -63.34 ± 2.03 and -61.52 ± 2.24 Kcal/mol, respectively.

Human pre-microRNA Expression Construct let-7a-1

PMIRHlet7a1PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7a-2

PMIRHlet7a2PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7a-3

PMIRHlet7a3PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7f-1

PMIRHlet7f1PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct let-7f-2

PMIRHlet7f2PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-96

PMIRH96PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-98

PMIRH98PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-21

PMIRH21PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-22

PMIRH22PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-28

PMIRH28PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-31

PMIRH31PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-32

PMIRH32PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-95

PMIRH95PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-99a

PMIRH99aPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-99b

PMIRH99bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-100

PMIRH100PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-107

PMIRH107PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-10a

PMIRH10aPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-10b

PMIRH10bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-122

PMIRH122PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-126

PMIRH126PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-127

PMIRH127PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-134

PMIRH134PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-137

PMIRH137PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-139

PMIRH139PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-140

PMIRH140PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-141

PMIRH141PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-142

PMIRH142PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-143

PMIRH143PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-144

PMIRH144PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-145

PMIRH145PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-147

PMIRH147PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-150

PMIRH150PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-151

PMIRH151PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-152

PMIRH152PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-154

PMIRH154AA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-154

PMIRH154PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-155

PMIRH155PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-15a

PMIRH15aPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-182

PMIRH182PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-183

PMIRH183PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-184

PMIRH184PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-185

PMIRH185PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-186

PMIRH186PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-187

PMIRH187PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-188

PMIRH188PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-18b

PMIRH18bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-190

PMIRH190PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-191

PMIRH191PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-192

PMIRH192PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-195

PMIRH195PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-197

PMIRH197PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-198

PMIRH198PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-202

PMIRH202PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-203

PMIRH203PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-204

PMIRH204PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-205

PMIRH205PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-206

PMIRH206PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-20b

PMIRH20bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-211

PMIRH211PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-214

PMIRH214PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-215

PMIRH215PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-217

PMIRH217PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-221

PMIRH221PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-222

PMIRH222PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-223

PMIRH223PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-224

PMIRH224PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-23a

PMIRH23aPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-23b

PMIRH23bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-26b

PMIRH26bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-296

PMIRH296AA-1 Miniprep DNA
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-296

PMIRH296PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-298

PMIRH298PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-299

PMIRH299PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-29c

PMIRH29cPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-300

PMIRH300PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-306

PMIRH306PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-30a

PMIRH30aPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-30b

PMIRH30bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-30d

PMIRH30dPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-30e

PMIRH30ePA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-323

PMIRH323PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-324

PMIRH324PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-325

PMIRH325PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-326

PMIRH326PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-328

PMIRH328PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-330

PMIRH330PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-331

PMIRH331PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-335

PMIRH335PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-337

PMIRH337PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-339

PMIRH339PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-33a

PMIRH33aPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-33b

PMIRH33bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-340

PMIRH340PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-342

PMIRH342PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-345

PMIRH345PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-346

PMIRH346PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-34a

PMIRH34aPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-34b

PMIRH34bPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-34c

PMIRH34cPA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-361

PMIRH361PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-362

PMIRH362PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-363

PMIRH363PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-367

PMIRH367AA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-367

PMIRH367PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-368

PMIRH368PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-370

PMIRH370PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-371

PMIRH371PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-372

PMIRH372PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-373

PMIRH373PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-375

PMIRH375PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-377

PMIRH377PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-378

PMIRH378PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-379

PMIRH379PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-380

PMIRH380PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-381

PMIRH381PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-382

PMIRH382PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-383

PMIRH383PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-384

PMIRH384PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-410

PMIRH410PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-411

PMIRH411PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-424

PMIRH424PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-425

PMIRH425PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-429

PMIRH429PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-431

PMIRH431PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-432

PMIRH432PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-433

PMIRH433PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-448

PMIRH448PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-452

PMIRH452PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-453

PMIRH453PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-454

PMIRH454PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-455

PMIRH455PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-483

PMIRH483PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-484

PMIRH484PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-485

PMIRH485PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-486

PMIRH486PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-488

PMIRH488PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-489

PMIRH489PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-490

PMIRH490PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-491

PMIRH491PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-492

PMIRH492PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-493

PMIRH493PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-494

PMIRH494PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-495

PMIRH495AA-1 Miniprep DNA
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-495

PMIRH495PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-496

PMIRH496PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-498

PMIRH498PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-499

PMIRH499PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-501

PMIRH501PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-503

PMIRH503PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-504

PMIRH504PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-505

PMIRH505PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-506

PMIRH506PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-507

PMIRH507PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-508

PMIRH508PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-510

PMIRH510PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-522

PMIRH522PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-523

PMIRH523PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-524

PMIRH524PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-525

PMIRH525PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-527

PMIRH527PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-532

PMIRH532PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-539

PMIRH539PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-541

PMIRH541PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-542

PMIRH542PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-543

PMIRH543PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-544

PMIRH544PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-545

PMIRH545PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-549

PMIRH549PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-552

PMIRH552PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-553

PMIRH553PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-554

PMIRH554PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-555

PMIRH555PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-556

PMIRH556PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-557

PMIRH557PA-1 Bacterial Streak
EUR 620

Human pre-microRNA Expression Construct Lenti-miR-558

PMIRH558PA-1 Bacterial Streak
EUR 620

The compounds additionally exhibited passable predicted ADMET profile and have been subjected to molecular dynamic (MD) research. The MD simulation produced secure complexes of those ligands with 3CLpro protein and ligand RMSD in acceptable limits. Communicated by Ramaswamy H. Sarma.

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